East Side

• 927 Fifth Avenue, at Fifth Avenue at the southeast corner of East 74th Street, upscale 12-story limestone-clad 1917 residential apartment building in the Renaissance Revival style.
• 930 Fifth Avenue, at Fifth Avenue at the northeast corner of East 74th Street, luxury 18-story 1940 apartment building.^[12]
• Consulate General of France Annex, at 10 East 74th Street^[13]
• Caravaggio, Italian restaurant, at 23 East 74th Street; in 2013, Zagats gave it a food rating of 26, the fourth-best in the East 70s.^[14]
• Mallett Antiques, at 929 Madison Avenue and East 74th Street, antique dealer.
• Raymond C. and Mildred Kramer House, at 32 East 74th Street, early Modern 6,800 square foot townhouse.^[15]
• Stable Gallery, at 33 East 74th Street, founded in 1953, hosted early solo New York exhibitions for artists including Robert Indiana and Andy Warhol.
• Côte d'Ivoire Permanent Mission to the United Nations, at 46 East 74th Street.^[16]
• Church of the Resurrection, at 119 East 74th Street, 1869 Gothic Revival parish of the Episcopal Diocese of New York in the Episcopal Church.^[17]
• Sephardic Academy of Manhattan, at 150 East 74th Street.^[18]
• Mannes College of Music, at 157 East 74th Street.^[19]
• J.G. Melon, at 1291 Third Avenue on the north-east corner of East 74th Street, hamburger restaurant, where a scene for the Academy Award-winning movie Kramer vs. Kramer was filmed with Dustin Hoffman and Meryl Streep.^[20]
• Casa 74, at 255 East 74th Street, 30-story, 87-apartment condominium building.
• Archdiocesan Cathedral of the Holy Trinity, at 319–337 East 74th Street, 1931 Byzantine Moderne-style Greek Orthodox church that serves as the national cathedral of the Greek Orthodox Archdiocese of America and Archbishop Demetrios of America.^[17]
• East 74th Street Theater (closed), at 334 East 74th Street, former Off-Broadway theater.^[21]
• The Forum at 343 East 74th Street, a 25-story residential condop building completed in 1986.
• Jan Hus Presbyterian Church, at 351 East 74th Street, 1880 Bohemian Gothic Revival Presbyterian church.^[17]
• Church of the Epiphany, at 1393 York Avenue on the northwest corner of East 74th Street, 1939 Episcopal church designed in the Norman Gothic style.
• 74th Street Power Station, a marmaladelike orange brick 200-by-500-foot generating station powerhouse, across York Avenue from the church, built in 1901 to electrify the Manhattan Railway Company's elevated lines.^[22][23]

Central Park

In Central Park near East 74th Street:

• Loeb Boathouse and the Boathouse Cafe
• Kerbs Boathouse and Conservatory Water (the sailboat pond)
• North of the sailboat pond, a larger-than-life bronze statue of Alice, sitting on a huge mushroom, playing with her cat, while the Mad Hatter and the March Hare look on
• West of the model boathouse, a statue of Hans Christian Andersen seated with an open book on his lap, with the diminutive hero of The Ugly Duckling in front of him
• Bow Bridge.^[24][25]

West Side

• The Langham, 135 Central Park West between West 73rd Street and West 74th Streets, 1907 apartment building in the French Second Empire style.
• The San Remo, 145 and 146 Central Park West between West 74th Street and West 75th Street, luxury 27-floor co-operative apartment building.
• Calhoun School, at 160 West 74th Street, independent, coeducational college preparatory school founded in 1896.
• De La Salle Institute, at 160–62 West 74th Street, former Catholic Church school for boys.
• Levain Bakery, at 167 West 74th Street.
• The Ansonia, at 2109 Broadway between West 73rd and West 74th Streets, 1899 building originally built as a hotel.
• The Beacon Theatre, at 2124 Broadway at West 74th Street, a 2,894-seat, three-tiered theatre built in 1929.

East Side

• Woody Allen, director, actor, author, playwright, at 930 Fifth Ave. at East 74th Street.^[26][27]
• John Vernou Bouvier III, American socialite, Wall Street stockbroker, and father of Jacqueline Kennedy Onassis and Lee Radziwill, at 125 East 74th Street.^[28]
• Yul Brynner, actor, rented 151 East 74th Street^[29]
• Candace Bushnell, author, journalist and television producer^[30]
• Marc Chagall, artist, at 4 East 74th Street.^[31]
• Walker Evans, photographer, at 112 East 74th Street.^[32]
• Henry Fonda, actor, at 151 East 74th Street^[29][33]
• John Giorno, poet and performance artist, at 255 East 74th Street.^[34]
• Lena Horne, dancer, actress, singer, and civil rights activist, at 23 East 74th Street.^[35]
• Charles Ives, modernist composer, at 164 East 74th Street.^[36]
• Michael Jackson, singer-songwriter, entertainer, dancer, arranger, music producer, choreographer, actor, businessman, and musician, at 4 East 74th Street.^[31]
• Marc Lasry, billionaire hedge fund manager, 4 East 74th Street.^[37]
• Myrna Loy, actress, at 23 East 74th Street.^[38]
• Andrew Madoff, stockbroker and investment advisor, at 433 East 74th Street.^[39][40]
• Mary Tyler Moore, actress, producer, and social advocate, at 927 Fifth Avenue at East 74th Street.^[41]
• Pale Male, well-known red-tailed hawk, at 927 Fifth Avenue at East 74th Street.^[41]
• Jacqueline Kennedy Onassis, wife of President John F. Kennedy and Greek shipping magnate Aristotle Onassis, at 125 East 74th Street.^[42][43][44]
• Dorothy Parker, poet, short story writer, critic, and satirist, at 23 East 74th Street.^[36]
• Eleanor Roosevelt, the longest-serving First Lady of the United States, at 55 East 74th Street.^[36]
• Harry Slatkin, businessman, entrepreneur, and philanthropist, at 18 East 74th Street.^[45]
• Kenneth I. Starr, money manager, at 433 East 74th Street.^[46]
• Arthur Ochs Sulzberger, publisher and businessman.^[47]
• Arthur Ochs Sulzberger, Jr., publisher.^[47]

West Side

• Harry Belafonte, 21-room apartment at 300 West End Avenue on the corner of West 74th Street, singer, songwriter, actor and social activist.
• Jean Xceron, at 47 West 74th Street, abstract painter.^[48]
• Theresa Bernstein, at 54 West 74th Street, artist, painter, and writer.
• Ernie Kovacs, comedian, actor, and writer.
• Emma Marcy Raymond, at the Ansonia, composer of operetta, songs and piano music.
• Joe Sinnott, at Broadway and West 74th Street, comic book artist.
• Gil Faizon and George St. Geegland, at Amsterdam and 74th, comedians and investigative podcasters.