Francesco Vettori (1474–1539) was an Italian diplomat, politician and writer from Florence. He served his city during both the republican and the de Medici regimes. He is remembered chiefly as one of the main personal correspondents of Niccolò Machiavelli, but he also published some small works himself in the same period.

Vettori's correspondence with Machiavelli includes some of the only surviving written discussions about the writing of Machiavelli's "little work", which was to become The Prince. The correspondence is considered to be amongst the most well known in Italian.

Other works by Vettori are a Sommario della istoria d'Italia ("Summary of the History of Italy") and a collection of stories called Viaggio in Alamagna ("Journey in Germany").

• Najemy, John (1993), Between Friends: Discourses of Power and Desire in the Machiavelli-Vettori Letters of 1513-1515, Princeton University Press
• Machiavelli, Niccolò (1996), Machiavelli and his friends: Their personal correspondence, Northern Illinois University Press. Translated and edited by James B. Atkinson and David Sices.
• Connell, William J. (2011), "New Light on Machiavelli's Letter to Vettori, 10 December 1513" (PDF), Europa e Italia. Studi in onore di Giorgio Chittolini / Europe and Italy. Studies in honour of Giorgio Chittolini: 93–127, archived from the original (PDF) on 26 April 2012, retrieved 20 October 2012.