Samuel Nicholson (1743–1811) was an officer in the Continental Navy and the United States Navy.

Samuel Nicholson may also refer to:

• Samuel Nicholson (merchant) (1738–1827), English wholesale haberdasher and banker
• Samuel Caldwell Nicholson (died 1891), British trade unionist
• Samuel D. Nicholson (1859–1923), United States Senator from Colorado
• Sam Nicholson (born 1995), Scottish footballer

• Nicholson (name)

This disambiguation page lists articles about people with the same name.
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