Santa Clara University College of Arts & Sciences is a private academic institution at Santa Clara University. It is the largest of the professional schools at Santa Clara University.

The College of Arts and Sciences at Santa Clara University offers degree programs in the arts, humanities, natural sciences, and social sciences, with interdisciplinary and cross-disciplinary options. As the home of the Core Curriculum, the College serves roughly 5,300 undergraduate students, 2,900 of whom are students within the College.

Made up of 27 departments and programs, the College offers 33 majors and 40 minors for undergraduate students and an M.A. in Pastoral Ministries for graduate students.^[7] It serves as the home of the Center for the Arts and Humanities^[8] and offers programming through various initiatives, including the Sinatra Chair in the Performing Arts,^[9] the Digital Humanities Initiative,^[10] and the DeNardo Lectureship in the Health Sciences.^[11]