How frontotemporal dementia, the syndrome affecting Bruce Willis, changes the brain – research is untangling its genetic causes
FTD leads to changes in personality and behavior. Understanding its genetic and molecular causes could lead to new ways to treat neurodegenerative diseases.
Fen-Biao Gao, Professor of Neurology, Gov. Paul Cellucci Chair in Neuroscience Research, UMass Chan Medical School
• conversation
Feb. 22, 2023 • ~8 min
Feb. 22, 2023 • ~8 min
ALS is only 50% genetic – identifying DNA regions affected by lifestyle and environmental risk factors could help pinpoint avenues for treatment
Genetic modifications to DNA regions involved in metabolism, cholesterol and immunity may play a role in ALS disease progression.
Paul J. Hop, PhD candidate in Neurogenetics, Utrecht University •
conversation
April 13, 2022 • ~5 min
April 13, 2022 • ~5 min
FDA-approved drug shows promise against ALS in mice
Accumulating evidence suggests that inflammatory processes may play a role in the initiation and progression of amyotrophic lateral sclerosis (ALS).
Harvard Gazette
• harvard
Nov. 27, 2019 • ~3 min
Nov. 27, 2019 • ~3 min
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