Chemists boost boron’s utility

A strategy for preventing boron-containing compounds from breaking down could help medicinal chemists design new drugs.

Anne Trafton | MIT News Office • mit
March 2, 2021 ~5 min

A little LSD makes mice more social. People too?

Scientists have discovered one of the possible mechanisms that lets LSD increase social interaction, at least in mice. It could lead to drugs for people.

Jason Clement-McGill • futurity
Jan. 28, 2021 ~5 min

The price of a drug should be based on its therapeutic benefits – not just what the market will bear

'Orphan drugs' with high price points are being tested as treatments for COVID-19. There's a better way to spur low-cost innovation for new drugs.

Nicole Hassoun, Professor of Philosophy, Binghamton University, State University of New York • conversation
Jan. 13, 2021 ~9 min

What is a margin of error? This statistical tool can help you understand vaccine trials and political polling

Whether you are predicting the outcome of an election or studying how effective a new drug is, there will always be some uncertainty. A margin of error is how statisticians measure that uncertainty.

Ofer Harel, Professor of Statistics, University of Connecticut • conversation
Jan. 6, 2021 ~5 min

RNA molecules are masters of their own destiny

Research suggests the products of transcription — RNA molecules — regulate their own production through a feedback loop.

Eva Frederick | Whitehead Institute • mit
Jan. 5, 2021 ~8 min

Turning microbiome research into a force for health

A diverse group of researchers is working to turn new discoveries about the trillions of microbes in the body into treatments for a range of diseases.

Zach Winn | MIT News Office • mit
Jan. 5, 2021 ~10 min

The top scientific breakthrough for 2020 was understanding SARS-CoV-2 and how it causes COVID-19 – and then developing multiple vaccines

The development of multiple vaccines against the virus that causes COVID-19 has been hailed as the breakthrough of 2020. But there were many more supporting discoveries that made this possible.

David Pride, Associate Director of Microbiology, University of California San Diego • conversation
Dec. 17, 2020 ~11 min

Tweaked psychedelic could treat depression and addiction

A non-hallucinogenic version of the psychedelic drug ibogaine called TBG has potential for treating addiction and depression, research with mice suggests.

Andy Fell-UC Davis • futurity
Dec. 14, 2020 ~5 min

SMART researchers use lysins to selectively target bacteria

The discovery can help to cure bacterial infections without inducing resistance or causing harm to good bacteria.

Singapore-MIT Alliance for Research and Technology • mit
Dec. 10, 2020 ~6 min

New antivenom would be cheap, fast, and easy to make

A new kind of antivenom would be far cheaper and easier to produce than current versions and super simple for people who've been bitten to use anywhere.

Søren Thiesen-Copenhagen • futurity
Nov. 30, 2020 ~7 min