Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.

Cambridge scientists have shown how the brain’s ability to clear out toxic proteins is impaired in Huntington’s disease and other forms of dementia – and how,

At an exhibition marking two decades since a transformative gift from the Picower Foundation, current and alumni members described research at the forefront of neuroscience and beyond.

Huntington's disease may result from defects in support cells called glia, say researchers. The discovery may put new therapies in reach.

A new mechanism that stops the progression of Huntington’s disease in cells has been identified by scientists at the University of Cambridge and UCL, as part

A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.

Opioid receptor MOR1 changes discovered in neurodegenerative disease model.

Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.

Artificial intelligence can check blood samples to predict and explain the progress of neurodegenerative diseases like Alzheimer's, researchers report.

Gifts to MIT and Harvard Medical School totaling $9 million will fund independent research on cannabinoid’s influence on brain health and behavior.