Understanding antibodies to avoid pandemics

Structural biologist Pamela Björkman shared insights into pandemic viruses as part of the Department of Biology’s IAP seminar series.

Saima Sidik | Department of Biology • mit
Jan. 19, 2021 ~5 min

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Likelihood of severe and ‘long’ COVID may be established very early on following infection

New research provides important insights into the role played by the immune system in preventing – and in some cases increasing the severity of – COVID-19

Cambridge University News • cambridge
Jan. 18, 2021 ~7 min

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10 reasons why Anthony Fauci was ready to be the face of the US pandemic response

2020 was a big year for Fauci – but he's been on the national stage for decades. Here's more about his work before COVID-19 and why he was perfectly poised to help the US respond to the pandemic.

Barbara Gastel, Professor of Veterinary Integrative Biosciences and of Humanities in Medicine, Texas A&M University • conversation
Dec. 17, 2020 ~10 min

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Remdesivir likely to be highly effective antiviral against SARS-CoV-2 for some patients

The drug remdesivir is likely to be a highly effective antiviral against SARS-CoV-2, according to a new study by a team of UK scientists. Writing in Nature

Cambridge University News • cambridge
Dec. 14, 2020 ~7 min

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Why it takes guts to protect the brain against infection

The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed

Cambridge University News • cambridge
Nov. 4, 2020 ~5 min

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Why males may have a worse response to COVID-19

A new study is the first to identify sex differences in inflammation and immune cell activation in response to SARS-CoV-2 infection, which causes COVID-19.

Meghan E. Rebuli, Assistant Professor of Pediatrics, University of North Carolina at Chapel Hill • conversation
Oct. 12, 2020 ~7 min

 health  medicine  covid-19  coronavirus  pandemic  immunology  flu  sars-cov-2  severe-acute-respiratory-syndrome-sars  immune-response  sex  middle-east-respiratory-syndrome

Older people like President Trump are at more risk from COVID-19 because of how the immune system ages

Older coronavirus patients face grimmer outlooks. A virologist explains the aging-related changes in how immune systems work that are to blame.

Brian Geiss, Associate Professor of Microbiology, Immunology & Pathology, Colorado State University • conversation
Oct. 2, 2020 ~7 min

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One small part of a human antibody has the potential to work as a drug for both prevention and therapy of COVID-19

Antibodies are great for neutralizing viruses. But they are big and bulky. Antibody engineers are now creating smaller synthetic antibody-like molecules that may be better for fighting COVID-19.

Dimiter Stanchev Dimitrov, Professor of Medicine and Director, Center for Antibody Therapeutics, University of Pittsburgh • conversation
Oct. 1, 2020 ~9 min

 health  medicine  immune-system  pandemic  immunology  sars-cov-2  covid-19-pandemic  ace2  antibody  innovation-and-invention  covid-19-research

Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA

Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.

David Orenstein | Picower Institute for Learning and Memory • mit
July 21, 2020 ~7 min

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Research highlights immune molecule’s complex role in Huntington’s disease

Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes.

David Orenstein | Picower Institute for Learning and Memory • mit
June 8, 2020 ~4 min

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