Five MIT faculty members take on Cancer Grand Challenges

Joining three teams backed by a total of $75 million, MIT researchers will tackle some of cancer’s toughest challenges.

Bendta Schroeder | Koch Institute • mit
March 18, 2024 ~4 min

Immune cells can adapt to invading pathogens, deciding whether to fight now or prepare for the next battle

When faced with a threat, T cells have the decision-making flexibility to both clear out the pathogen now and ready themselves for a future encounter.

Hao Yuan Kueh, Associate Professor of Bioengineering, University of Washington • conversation
March 8, 2024 ~6 min


Blood cell family trees trace how production changes with aging

Whitehead Institute Member Jonathan Weissman and collaborators developed a tool to reconstruct human cell family trees, revealing how blood cell production changes in old age.

Greta Friar | Whitehead Institute • mit
Jan. 31, 2024 ~11 min

Simons Center’s collaborative approach propels autism research, at MIT and beyond

Team-based targeted projects, multi-mentor fellowships ensure that scientists studying social cognition, behavior, and autism integrate multiple perspectives and approaches to pressing questions.

David Orenstein | Simons Center for the Social Brain • mit
Jan. 30, 2024 ~12 min

What if every germ hit you at the exact same time? An immunologist explains

Your immune system is often able to fend off pathogens it’s never seen before. But defending your body against all of them all at once is a tough challenge.

Joseph Larkin III, Associate Professor of Microbiology and Cell Science, University of Florida • conversation
Jan. 15, 2024 ~8 min

Drugs of the future will be easier and faster to make, thanks to mRNA – after researchers work out a few remaining kinks

The COVID-19 pandemic demonstrated the promise of using mRNA as medicine. But before mRNA drugs can go beyond vaccines, researchers need to identify the right diseases to treat.

Li Li, Assistant Professor of Biomedical Sciences, UMass Chan Medical School • conversation
Jan. 4, 2024 ~9 min

Immune action at a distance

MIT and MGH researchers design a local, gel-based drug-delivery platform that may provoke a system-wide immune response to metastatic tumors.

Bendta Schroeder | Koch Institute • mit
Nov. 30, 2023 ~10 min

How do viruses get into cells? Their infection tactics determine whether they can jump species or set off a pandemic

Viruses can get into cells in several ways. Figuring out how to stop them from entering in the first place is a key to developing better vaccines and stopping future pandemics.

Peter Kasson, Professor of Molecular Physiology and Biomedical Engineering, University of Virginia • conversation
Nov. 21, 2023 ~6 min


Immune health is all about balance – an immunologist explains why both too strong and too weak an immune response can lead to illness

Dietary supplements claim to be able to ‘boost your immune system’ to combat disease. But attaining immune balance through a healthy lifestyle and vaccination is a safer bet to keep in good health.

Aimee Pugh Bernard, Assistant Professor of Immunology and Microbiology, University of Colorado Anschutz Medical Campus • conversation
Nov. 20, 2023 ~6 min

An itching paradox – a molecule that triggers the urge to scratch also turns down inflammation in the skin

Itch-sensing neurons in your skin are intertwined with your immune cells. Counterintuitively, the molecule that connects them triggers responses that both worsen and improve skin conditions.

Marlys Fassett, Associate Professor of Dermatology, University of California, San Francisco • conversation
Oct. 13, 2023 ~7 min

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