Coronavirus and cancer hijack the same parts in human cells to spread – and our team identified existing cancer drugs that could fight COVID-19

Kinases are cellular control switches. When they malfunction, they can cause cancer. The coronavirus hijacks these kinases to replicate, and cancer drugs that target them could fight COVID-19.

Nevan Krogan, Professor and Director of Quantitative Biosciences Institute & Senior Investigator at the Gladstone Institutes, University of California, San Francisco • conversation
June 28, 2020 ~10 min

Tags: drugs covid-19 coronavirus sars-cov-2 treatment antiviral-drugs drug-research sars-cov mass-spectrometry cancer-drugs antiviral

Scientists tap the world's most powerful computers in the race to understand and stop the coronavirus

Scanning through billions of chemicals to find a few potential drugs for treating COVID-19 requires computers that harness together thousands of processors.

Jeremy Smith, Governor's Chair, Biophysics, University of Tennessee • conversation
June 3, 2020 ~9 min

Tags: medicine drug-discovery covid-19 coronavirus pandemic molecular-biology antiviral-drugs viruses computational-biology proteins sars-cov2 biophysics drug supercomputers

Could chloroquine treat coronavirus? 5 questions answered about a promising, problematic and unproven use for an antimalarial drug

A medicinal chemist addresses questions about chloroquine and hydroxychloroquine: what it is, whether it is effective against COVID-19 and whether it can treat and/or prevent this disease.

Katherine Seley-Radtke, Professor of Chemistry and Biochemistry and President-Elect of the International Society for Antiviral Research, University of Maryland, Baltimore County • conversation
March 25, 2020 ~6 min

Tags:  covid-19  antiviral-drugs  viruses  sars-cov  mers-cov  antimalarial

COVID-19 treatment might already exist in old drugs – we're using pieces of the coronavirus itself to find them

Among the more than 20,000 drugs approved by the FDA, there may be some that can treat COVID-19. A team at the University of California, San Francisco, is identifying possible candidates.

Nevan Krogan, Professor and Director of Quantitative Biosciences Institute, University of California, San Francisco • conversation
March 20, 2020 ~8 min

Tags:  drugs  drug-discovery  covid-19  coronavirus  fda  sars-cov-2  treatment  disease  antiviral-drugs  viruses  viral-infections  drug-research

Page 1 of 1