Nobel Prize for chemistry honors exquisitely precise gene-editing technique, CRISPR – a gene engineer explains how it works

The tools to rewrite the genetic code to improve crops and livestock, or to treat genetic diseases, has revolutionized biology. A CRISPR engineer explains why this technology won the Nobel, and its potential.

Piyush K. Jain, Assistant Professor of Chemical Engineering, Herbert Wertheim College of Engineering, UF Health Cancer Center, University of Florida • conversation
Oct. 7, 2020 ~8 min

 crispr  nobel-prize  agriculture  gene-editing  nobel-prize-2020  nobel-prize-in-chemistry  gene-edited-babies  gene-edited-livestock

Nobel Prize for CRISPR honors two great scientists – and leaves out many others

Most scientific discoveries these days aren't easily ascribed to a single researcher. CRISPR is no different – and ongoing patent fights underscore how messy research can be.

Marc Zimmer, Professor of Chemistry, Connecticut College • conversation
Oct. 7, 2020 ~9 min

dna crispr gene-editing genome-editing crisprcas patents nobel-prize-2020 crisprcas9 yogurt nobel-prize-in-chemistry

CRISPR can help combat the troubling immune response against gene therapy

The immune system is trained to destroy viruses, even when they carry therapeutic cargo as is the case in gene therapy. Now researchers have figured out how to dial down the immune response.

Samira Kiani, Associate Professor of Pathology, University of Pittsburgh • conversation
Sept. 3, 2020 ~7 min

 innovation  health  medicine  crispr  inflammation  immune-system  gene-therapy  gene-editing  viruses  steroids

How gene editing a person's brain cells could be used to curb the opioid epidemic

A person dies of opioid overdose once every 13 minutes in the US. A researcher proposes a way using existing technology to remove the opioid target in people to prevent overdoses.

Craig W. Stevens, Professor of Pharmacology, Oklahoma State University • conversation
Aug. 5, 2020 ~9 min

 crispr  opioid  gene-editing  morphine  crisprcas  endorphins  analgesic  oxycodone

Gene therapy and CRISPR strategies for curing blindness (Yes, you read that right)

Strategies to cure various types of blindness are looking more plausible after a series of recent breakthroughs using gene editing and gene therapy.

Hemant Khanna, Associate Professor of Ophthalmology, University of Massachusetts Medical School • conversation
June 25, 2020 ~9 min

 gene-therapy  blindness  gene-editing  vision  infrared  eye  crisprcas

Ethicists: We need more flexible tools for evaluating gene-edited food

What criteria should be used to determine whether a food is natural? What if gene-editing techniques produce changes indistinguishable from those that evolve naturally? Is the food still natural?

Trine Antonsen, Resarch Scientist at GenØk Centre for Biosafety and Associate Professor, University of Tromsø • conversation
May 26, 2020 ~8 min

gene-editing organic genetically-modified-organisms species genetically-modified-crops natural genetically-modified