COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

Are antibodies that attack a patient's own organs contributing to severe forms of COVID-19? A new study suggests specific antibody tests that may reveal the answer.

Matthew Woodruff, Instructor, Lowance Center for Human Immunology, Emory University • conversation
yesterday ~8 min

Tags: covid-19 immune-system pandemic antibodies sars-cov-2 viruses autoimmune-diseases autoimmune-illness

Exposure to man-made chemicals influences genes controlling aging, immune system and metabolism

Man-made chemical disrupt the activities of most human genes. What effect does this have on human health and how should regulators respond?

Alexander Suvorov, Assistant Professor, University of Massachusetts Amherst • conversation
Oct. 15, 2020 ~8 min

Tags: health environment metabolism obesity immune-system genes toxicology

An autoimmune-like antibody response is linked with severe COVID-19

Patients suffering from severe COVID-19 may be experiencing a rogue antibody response similar to that seen in autoimmune diseases. The findings offer new approaches for COVID-19 therapy.

Matthew Woodruff, Instructor, Lowance Center for Human Immunology, Emory University • conversation
Oct. 8, 2020 ~8 min

Tags:  covid-19  immune-system  pandemic  sars-cov-2  viruses  infection  cytokine-storm  antibody  autoimmune-diseases  b-cell

Older people like President Trump are at more risk from COVID-19 because of how the immune system ages

Older coronavirus patients face grimmer outlooks. A virologist explains the aging-related changes in how immune systems work that are to blame.

Brian Geiss, Associate Professor of Microbiology, Immunology & Pathology, Colorado State University • conversation
Oct. 2, 2020 ~7 min

Tags: covid-19 coronavirus immune-system t-cells immunology aging donald-trump sars-cov-2 immunity adaptive-immune-response innate-immune-response immune-response white-blood-cells t-cell immune-function coronavirus-pandemic diagnostic-test

One small part of a human antibody has the potential to work as a drug for both prevention and therapy of COVID-19

Antibodies are great for neutralizing viruses. But they are big and bulky. Antibody engineers are now creating smaller synthetic antibody-like molecules that may be better for fighting COVID-19.

Dimiter Stanchev Dimitrov, Professor of Medicine and Director, Center for Antibody Therapeutics, University of Pittsburgh • conversation
Oct. 1, 2020 ~9 min

Tags:  health  medicine  immune-system  pandemic  immunology  sars-cov-2  covid-19-pandemic  ace2  antibody  innovation-and-invention  covid-19-research

How and when will we know that a COVID-19 vaccine is safe and effective?

Several vaccines are in Phase 3 trials. So when will we know whether any of these will protect against COVID-19?

William Petri, Professor of Medicine, University of Virginia • conversation
Sept. 22, 2020 ~10 min

Tags: covid-19 immune-system pandemic fda vaccines sars-cov-2 phase-3-trial immune-response vaccine-trials covid-19-vaccine vaccine-safety vaccine-approval

Good nutrition can contribute to keeping COVID-19 and other diseases away

Many of us don't get an adequate amount of nutrients.

Grayson Jaggers, Assistant Professor (Teaching) of Biological Sciences, University of Southern California • conversation
Sept. 17, 2020 ~7 min

Tags:  health  diet  covid-19  coronavirus  obesity  immune-system  food  nutrition  junk-food

Steroids cut COVID-19 death rates, but not for everyone – here’s who benefits and who doesn’t

Three new studies show corticosteroids can reduce deaths in critically ill COVID-19 patients. But what about other patients?

Bryan McVerry, Associate Professor of Medicine, University of Pittsburgh • conversation
Sept. 4, 2020 ~8 min

Tags: medicine covid-19 coronavirus immune-system biology pandemic science hospitals research icu medication steroids

CRISPR can help combat the troubling immune response against gene therapy

The immune system is trained to destroy viruses, even when they carry therapeutic cargo as is the case in gene therapy. Now researchers have figured out how to dial down the immune response.

Samira Kiani, Associate Professor of Pathology, University of Pittsburgh • conversation
Sept. 3, 2020 ~7 min

Tags:  innovation  health  medicine  crispr  inflammation  immune-system  gene-therapy  gene-editing  viruses  steroids

Declining antibodies and immunity to COVID-19 – why the worry?

If antibody levels drop dramatically after an infection, what does that mean for immunity? An expert explains how B and T cells contribute to immunity and why antibodies don't tell the full story.

Alexander (Sasha) Poltorak, Professor of Immunology, Tufts University • conversation
Aug. 26, 2020 ~7 min

Tags: covid-19 immune-system pandemic sars-cov-2 adaptive-immune-response innate-immune-response immune-response t-cell antibody b-cell

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