How spit gets its ‘army’ of proteins

A new paper maps out how saliva gets its many proteins. It's a baseline for further investigations into spit as diagnostic fluid.

Charlotte Hsu-Buffalo • futurity
Nov. 20, 2020 ~6 min

enzymes proteins health-and-medicine mouth saliva

Tweaked enzyme may treat spine injury and stroke damage

An enzyme called chondroitinase ABC that regrows damaged nerve tissue in animals has been too unstable for human use. New work could change things.

Jim Barlow-Oregon • futurity
Sept. 8, 2020 ~6 min

stroke neurons enzymes health-and-medicine traumatic-injury spinal-cord

Tuning PARP inhibitor drug amps up its cancer-killing power

With modification a PARP inhibitor drug that's struggled in clinical trials kills cancer much more effectively, researchers say.

Melissa Moody-Penn • futurity
April 10, 2020 ~5 min

dna cancer enzymes health-and-medicine medications

1 enzyme is key for successful fertilization

One enzyme may determine whether human development starts correctly. The discovery could help explain why some fertilization fails.

Mathias Traczyk-Copenhagen • futurity
April 3, 2020 ~3 min

genes enzymes eggs fetus health-and-medicine sperm fertilization

Method reprograms cells to build stuff on brain cells

A new technique called genetically targeted chemical assembly reprograms cells to build artificial structures to carry out functions inside the body.

Stanford • futurity
March 23, 2020 ~4 min

autism neurons brains enzymes epilepsy health-and-medicine

Filaments are weapons in ‘world’s oldest war’

New research shows how a once-forgotten cellular structure fights in the "world’s oldest war," the battle between bacteria and viruses.

Mikayla Mace-Arizona • futurity
Dec. 4, 2019 ~5 min

dna bacteria enzymes viruses cells science-and-technology

Next antibiotic may come from dirt bacteria

"...we really need new structural classes of antibiotics that have never been contaminated by clinical resistance from established antibiotic classes."

Talia Ogliore-WUSTL • futurity
Aug. 2, 2019 ~7 min

bacteria soil antibiotics drug-resistance enzymes drug-development featured health-and-medicine

Enzyme in blood of young mice slows aging in older ones

"We were surprised by the dramatic differences between the old mice that received the eNAMPT of young mice and old mice that received saline as a control."

Julia Evangelou Strait-WUSTL • futurity
June 17, 2019 ~6 min

aging enzymes blood featured health-and-medicine lifespan

Our love of starch changed our genes (and our spit)

Mammals with starchy diets—us, dogs, and rats, as opposed to, say, hedgehogs and mountain lions—appear to have adapted, genetically, to stomach more carbs.

Charlotte Hsu-Buffalo • futurity
May 15, 2019 ~8 min

evolution mammals food enzymes featured science-and-technology saliva

‘Extra’ enzymes boost E. coli resistance at low pH

Studying E. coli at neutral pH in the lab might not give us a full sense of their powers against antibiotics.

Talia Ogliore-WUSTL • futurity
April 15, 2019 ~4 min

bacteria drug-resistance enzymes e-coli health-and-medicine urinary-tract-infections

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