New drug prolongs ALS patient survival in trial

An experimental medication that was recently shown to slow the progression of ALS has now demonstrated the potential to also prolong patient survival.

Harvard Gazette • harvard
Oct. 16, 2020 ~4 min

Tags: harvard-medical-school health-medicine als massachusetts-general-hospital mgh lou-gehrigs-disease sean-m-healey-amg-center-for-als

Harvard scientists identify gut-brain connection in ALS

The researchers found that in mice with a common ALS genetic mutation, changing the gut microbiome could prevent or improve disease symptoms.

Jessica Lau • harvard
May 13, 2020 ~5 min

Tags: science-technology inflammation als gut-microbiome amyotrophic-lateral-sclerosis gut-brain-axis

FDA-approved drug shows promise against ALS in mice

Accumulating evidence suggests that inflammatory processes may play a role in the initiation and progression of amyotrophic lateral sclerosis (ALS).

Harvard Gazette • harvard
Nov. 27, 2019 ~3 min

Tags:  inflammation  basic-research  health-medicine  als  amyotrophic-lateral-sclerosis  cromolyn-sodium

Exercise, fasting shown to help cells shed defective proteins

A new study from the Blavatnik Institute finds that intense exercise and fasting activate hormones that boost cells’ capacity to dispose of defective proteins, which clog up the cell, interfere with its functions, and, over time, precipitate diseases including neurodegenerative conditions such as ALS and Alzheimer’s.

Ekaterina Pesheva • harvard
Feb. 21, 2019 ~9 min

Tags:  exercise  harvard-medical-school  health-medicine  hms  alfred-goldberg  als  alzheimers  blavatnik-institute  fasting  hormones  human-cells  mouse-cells  muscular-dystrophy  nih  toxic-proteins

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