Human knee evolved in lockstep with osteoarthritis, Harvard study says

In a new paper published in Cell, Harvard researchers exploring the genetic features that help make the knee possible found that the regulatory switches involved in its development also play a role in a partially heritable disease.

Clea Simon • harvard
April 7, 2020 ~5 min

 cell  health-medicine  human-evolutionary-biology  harvard-study-says  knee  terence-capellini

Harvard Medical School develops AI to see visual cortex’s preferences

New computer program uses artificial intelligence to determine what visual neurons like to see. The approach could shed light on learning disabilities, autism spectrum disorders, and other neurologic conditions.

Christy Brownlee • harvard
May 2, 2019 ~5 min

 science-technology  artificial-intelligence  cell  ai  harvard-medical-school  hms  blavatnik-institute  neurobiology  macaques  margaret-livingstone  will-xiao

Brigham, Broad Institute researchers ID molecules that rein in CRISPR systems

Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.

Karen Zusi • harvard
May 2, 2019 ~5 min

 science-technology  crispr  cell  brigham-and-womens-hospital  gene-editing  amit-choudhary  broad-institute  cas-enzymes

Harvard researchers explore macular degeneration through a new lens

Researchers have created the first cellular atlas of the primate retina and discovered that, while the fovea and peripheral retina share most of the same cell types, the cells are in different proportions, and show different gene expression patterns.

Peter Reuell • harvard
Feb. 21, 2019 ~6 min

 science-technology  cell  faculty-of-arts-and-sciences  fas  harvard  peter-reuell  reuell  neurons  retina  visual-perception  diabetic-macular-edema  fovea  josh-sanes  macula  macular-degeneration  primates  sanes  vision  vision-related-diseases

Harvard research challenges conventional thinking on cell membranes

Harvard’s Adam Cohen is the lead author of a new study that challenges conventional theories about the fluid nature of cell membranes and how they react to tension.

Peter Reuell • harvard
Nov. 8, 2018 ~6 min

 science-technology  cell  faculty-of-arts-and-sciences  fas  harvard  peter-reuell  adam-cohen  cell-signaling  cohen  jell-o  membrane  shi  tension  tension-signaling  trans-membrane-proteins  zheng-shi

Harvard research challenges conventional thinking on cell membranes

Harvard’s Adam Cohen is the lead author of a new study that challenges conventional theories about the fluid nature of cell membranes and how they react to tension.

Peter Reuell • harvard
Nov. 8, 2018 ~6 min

 science-technology  cell  faculty-of-arts-and-sciences  fas  harvard  peter-reuell  adam-cohen  cell-signaling  cohen  jell-o  membrane  shi  tension  tension-signaling  trans-membrane-proteins  zheng-shi

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