After his wife was diagnosed with Alzheimer’s, Arthur Kleinman shares what he learned

Harvard Professor Arthur Kleinman’s wife, Joan, began to struggle with a rare form of early Alzheimer’s disease at 59. Eight years after losing her, he chronicles their journey in “The Soul of Care: The Moral Education of a Husband and a Doctor.”

Jill Radsken
Oct. 31, 2019 | harvard

~10 mins   

Tags: health-medicine the-soul-of-care alzheimers arthur-kleinman caregiving fas health-care hms jill-radsken medical-anthropology psychiatry

Harvard undergrad Michael Chen works at the corner of med and tech

Undergraduate Michael Chen, who created an extraordinary program to help treat TB, also works with a student program to treat ordinary patients.

Jill Radsken
Aug. 9, 2019 | harvard

~5 mins   

Tags: health-medicine andrew-beam applied-math biology biomedical-informatics-lab crimson-care-collaborative fas hms isaac-kohane jill-radsken maha-farhat medical-technology michael-chen sean-eddy tuberculosis

Harvard scientists uncover key allowing deadly viruses to replicate

Scientists uncover a key mechanism that allows some of the deadliest human RNA viruses to replicate, and it resides in the tail end of the viruses. The findings identify new targets to inhibit viral replication and may inform the development of a new class of antiviral drugs.

Ekaterina Pesheva
May 17, 2019 | harvard

~5 mins   

Tags: health-medicine blavatnik-institute bunyaviruses harvard-medical-school hms jess-pyle la-crosse-virus lassa-fever-virus machupo-virus rift-valley-fever rna-virus sean-pj-whelan

Harvard undergrad’s AI model helps to predict TB resistance

A Harvard undergrad, working with Harvard Medical School scientists, has designed an artificial intelligence model that predicts tuberculosis resistance to 10 most commonly used drugs. The new model outperforms previous machine-learning tools, and incorporating it into clinical tests could dramatically enhance early detection and prompt treatment of drug-resistant TB.

Ekaterina Pesheva
May 2, 2019 | harvard

~11 mins   

Tags: science-technology akshith-doddi analysis-group andy-beam bill-and-melinda-gates-foundation blavatnik-institute critical-path-institute drug-resistance ebiomedicine gentb harvard-medical-school harvard-th-chan-school-of-public-health hms isaac-kohane jimmy-royer luca-freschi marco-schito masha-farhat massachusetts-general-hospital matthew-ezewudo mdr-tb mgh michael-chen tb tuberculosis university-of-virginia-school-of-medicine xdr-tb

Harvard Medical School develops AI to see visual cortex’s preferences

New computer program uses artificial intelligence to determine what visual neurons like to see. The approach could shed light on learning disabilities, autism spectrum disorders, and other neurologic conditions.

Christy Brownlee
May 2, 2019 | harvard

~5 mins   

Tags: science-technology ai artificial-intelligence blavatnik-institute cell harvard-medical-school hms macaques margaret-livingstone neurobiology will-xiao

Harvard undergrad’s AI model predicts TB resistance

A Harvard undergrad, working with Harvard Medical School scientists, has designed an artificial intelligence model that predicts tuberculosis resistance to 10 most commonly used drugs. The new model outperforms previous machine-learning tools, and incorporating it into clinical tests could dramatically enhance early detection and prompt treatment of drug-resistant TB.

Ekaterina Pesheva
May 2, 2019 | harvard

~11 mins   

Tags: science-technology akshith-doddi analysis-group andy-beam bill-and-melinda-gates-foundation blavatnik-institute critical-path-institute drug-resistance ebiomedicine gentb harvard-medical-school harvard-th-chan-school-of-public-health hms isaac-kohane jimmy-royer luca-freschi marco-schito masha-farhat massachusetts-general-hospital matthew-ezewudo mdr-tb mgh michael-chen tb tuberculosis university-of-virginia-school-of-medicine xdr-tb

Harvard geneticist: No population’s DNA is ‘pure’

Geneticist David Reich discusses DNA findings that show how migration shaped Europe and southern Asia, and that “No population is, or ever could be, pure.”

Brett Milano
Feb. 28, 2019 | harvard

~5 mins   

Tags: science-technology ancient-humans brett-milano david-reich dna genetics harvard-medical-school hms migration

With two major exceptions, overlapping surgeries are safe overall

Overlapping surgeries, in which more than one doctor performs sequential surgeries in different operating rooms, have raised concerns about potential adverse outcomes — but a new analysis shows they carry no greater risk for low-risk, noncardiac patients.

Jake Miller
Feb. 26, 2019 | harvard

~7 mins   

Tags: health-medicine cardiac-bypass coronary-artery-bypass ekaterina-peshava harvard-medical-school high-risk-patients hms overlapping-surgeries surgeons

Exercise, fasting shown to help cells shed defective proteins

A new study from the Blavatnik Institute finds that intense exercise and fasting activate hormones that boost cells’ capacity to dispose of defective proteins, which clog up the cell, interfere with its functions, and, over time, precipitate diseases including neurodegenerative conditions such as ALS and Alzheimer’s.

Ekaterina Pesheva
Feb. 21, 2019 | harvard

~9 mins   

Tags: health-medicine alfred-goldberg als alzheimers blavatnik-institute exercise fasting harvard-medical-school hms hormones human-cells mouse-cells muscular-dystrophy nih toxic-proteins

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