The Wyss Institute and Roche Innovation Center Basel in Switzerland have teamed up to create 3-D bioprinted proximal tubules beside functioning blood vessel compartments, closely mimicking the kidney’s blood-filtration system that removes waste products while returning “good” molecules, such as glucose and amino acids, back into the bloodstream.

By exposing stem cell-derived kidney organoids to fluidic shear stress, A team of Harvard researchers has significantly expanded the organoids’ vascular networks and improved the maturation of kidney compartments.