MGH-led study shows light therapy is safe

MGH-led study shows light therapy is safe, modulates brain repair, and may benefit patients with moderate traumatic brain injury.

Harvard Gazette • harvard
Sept. 23, 2020 ~8 min

Tags: harvard-medical-school health-medicine hms massachusetts-general-hospital mgh benjamin-vakoc light-therapy rajiv-gupta

Losing a pet can affect children’s mental health, study finds

Mass. General study finds that the loss of a pet can potentially trigger mental health issues in children.

Harvard Gazette • harvard
Sept. 10, 2020 ~5 min

Tags: children mental-health death pets health-medicine mgh grief mass-general-hospital

Mass. General tests new therapy for pregnant coronavirus patients

Mass General study shows the benefits of inhaled nitric oxide therapy for pregnant patients with severe and critical COVID-19.

Harvard Gazette • harvard
Aug. 26, 2020 ~6 min

Tags: covid-19 coronavirus pregnancy health-medicine mgh nitric-oxide mass-general-hospital

Removing the constraining requirements at gene editing site

Investigators at Massachusetts General Hospital have modified the gene editing system, making it possible to potentially target any location across the entire human genome.

Harvard Gazette • harvard
March 26, 2020 ~3 min

Tags:  science-technology  crispr  cancer  basic-research  mgh  blindness  gene-editing  benjamin-p-kleinstiver  cas9  center-for-genomic-medicine

Special ice solution injected under skin is shown to reduce fat

The lab that invented cryolipolisis or “Coolsculpting,” a popular nonsurgical method for reducing fat under the skin, is developing a promising new form of the technology that can selectively reduce fat almost anywhere in the body using an injectable ice solution or “slurry.”

Harvard Gazette • harvard
Jan. 15, 2020 ~5 min

Tags:  basic-research  health-medicine  mgh  lilit-garibyan  wellman-center-for-photomedicine  coolsculpting  cryolipolisis  fat-cells  fat-deposits

Trial shows antihypertension drug may improve pancreatic cancer outcomes

Adding the blood-pressure drug losartan to the intensive chemo and radiation protocol for treating locally advanced pancreatic cancer allowed complete removal of the tumor in 61 percent of trial participants and significantly improved survival rates.

Sue McGreevey • harvard
May 30, 2019 ~5 min

Tags:  health-medicine  massachusetts-general-hospital  mgh  blood-pressure  carlos-fernandez-del-castillo  janet-murphy  jennifer-wo  losartan  pancreatic-cancer  rakesh-k-jain  theodore-hang

Mass. General researchers develop 3-D ‘mini-gut’ model to study response to gluten

Researchers at Massachusetts General Hospital have created miniature, simplified versions of the intestine in vitro to explore how the gut lining and microbiome respond to gluten in both healthy and celiac patients.

Susie Flaherty • harvard
May 9, 2019 ~4 min

Tags:  health-medicine  massachusetts-general-hospital  mgh  organoids  gluten  alessio-fasano  anna-sapone  anthony-anselmo  celiac-disease  gloria-serena  laura-ingano  mass-general  mibrc  mucosal-immunology-and-biology-research-center  murat-cetinbas  rachel-freire  ruslan-sadreyev  stefania-senger

Harvard undergrad’s AI model helps to predict TB resistance

A Harvard undergrad, working with Harvard Medical School scientists, has designed an artificial intelligence model that predicts tuberculosis resistance to 10 most commonly used drugs. The new model outperforms previous machine-learning tools, and incorporating it into clinical tests could dramatically enhance early detection and prompt treatment of drug-resistant TB.

Ekaterina Pesheva • harvard
May 2, 2019 ~11 min

Tags:  science-technology  harvard-medical-school  hms  blavatnik-institute  harvard-th-chan-school-of-public-health  massachusetts-general-hospital  mgh  akshith-doddi  analysis-group  andy-beam  bill-and-melinda-gates-foundation  critical-path-institute  drug-resistance  ebiomedicine  gentb  isaac-kohane  jimmy-royer  luca-freschi  marco-schito  masha-farhat  matthew-ezewudo  mdr-tb  michael-chen  tb  tuberculosis  university-of-virginia-school-of-medicine  xdr-tb

Harvard undergrad’s AI model predicts TB resistance

A Harvard undergrad, working with Harvard Medical School scientists, has designed an artificial intelligence model that predicts tuberculosis resistance to 10 most commonly used drugs. The new model outperforms previous machine-learning tools, and incorporating it into clinical tests could dramatically enhance early detection and prompt treatment of drug-resistant TB.

Ekaterina Pesheva • harvard
May 2, 2019 ~11 min

Tags:  science-technology  harvard-medical-school  hms  blavatnik-institute  harvard-th-chan-school-of-public-health  massachusetts-general-hospital  mgh  akshith-doddi  analysis-group  andy-beam  bill-and-melinda-gates-foundation  critical-path-institute  drug-resistance  ebiomedicine  gentb  isaac-kohane  jimmy-royer  luca-freschi  marco-schito  masha-farhat  matthew-ezewudo  mdr-tb  michael-chen  tb  tuberculosis  university-of-virginia-school-of-medicine  xdr-tb

76 more gene regions found associated with sleep duration

Scientists from Massachusetts General Hospital and the University of Exeter Medical School have identified another 76 gene regions associated with sleep duration. Their findings may underpin future investigations into disordered sleep and understanding individual set points for how much is enough.

Sue McGreevey • harvard
March 8, 2019 ~6 min

Tags:  health-medicine  massachusetts-general-hospital  mgh  nature-communications  early-riser  genome-wide-association-study  hassan-saeed-dashti  night-owl  richa-saxena  samuel-jones  uk-biobank  university-of-exeter-medical-school

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