Researchers unveil stem cell models of human spine development

Harvard researchers have unveiled the first stem cell models of human spine development, setting the stage for better understanding of musculoskeletal and metabolic disorders, including congenital scoliosis, muscular dystrophy, and Type 2 diabetes.

Stephanie Dutchen • harvard
Jan. 8, 2020 ~6 min

Tags:  science-technology  stem-cells  type-2-diabetes  muscular-dystrophy  congenital-scoliosis  musculoskeletal-disorders  olivier-pourquie  segmentation-clock

Exercise, fasting shown to help cells shed defective proteins

A new study from the Blavatnik Institute finds that intense exercise and fasting activate hormones that boost cells’ capacity to dispose of defective proteins, which clog up the cell, interfere with its functions, and, over time, precipitate diseases including neurodegenerative conditions such as ALS and Alzheimer’s.

Ekaterina Pesheva • harvard
Feb. 21, 2019 ~9 min

Tags:  exercise  harvard-medical-school  health-medicine  hms  alfred-goldberg  als  alzheimers  blavatnik-institute  fasting  hormones  human-cells  mouse-cells  muscular-dystrophy  nih  toxic-proteins

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