A connection between ancestry and the molecular makeup of cancer

A new study takes the most comprehensive look to date at the connection between the ancestry and the molecular makeup of cancer.

Rob Levy • harvard
May 11, 2020 ~7 min

Tags: cancer basic-research health-medicine tumors broad-institute human-genome-project ancestry nci-cancer-genome-analysis-network

Novel drug targets tumor growth in advanced kidney cancer

Harvard researchers at Dana-Farber Cancer Institute have developed a novel targeted drug that shows promise in advanced kidney cancer by interfering with the abnormal blood vessel formation that fuels tumor growth.

Richard Saltus • harvard
Feb. 12, 2020 ~4 min

Tags:  nobel-prize  basic-research  health-medicine  dana-farber-cancer-institute  tumors  clear-cell-renal-cell-carcinoma  hypoxia-inducible-factor  kidney-cancer  metastatic-disease  mk-6482  phase-iii  toni-choueiri  william-g-kaelin-jr

Exposing how pancreatic cancer does its dirty work

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell • harvard
Aug. 28, 2019 ~8 min

Tags:  science-technology  engineering  basic-research  harvards-wyss-institute-for-biologically-inspired-engineering  tumors  pancreatic-cancer  angiogenesis  cancer-cells  endothelial-cells  immune-cells  organ-on-chip

Solution to pancreatic cancer puzzle is discovered

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell • harvard
Aug. 28, 2019 ~8 min

Tags:  science-technology  harvards-wyss-institute-for-biologically-inspired-engineering  tumors  pancreatic-cancer  angiogenesis  cancer-cells  endothelial-cells  immune-cells  organ-on-chip

Platelet ‘decoys’ outsmart both clots and cancer

A team of researchers at the Wyss Institute at Harvard University and several collaborating institutions has created a drug-free, reversible antiplatelet therapy that uses deactivated “decoy” platelets to reduce the risk of blood clots and potentially prevent cancer metastasis.

Lindsay Brownell • harvard
Feb. 13, 2019 ~8 min

Tags:  health-medicine  activated-platelets  antiplatelet-drugs  blood-clots  deactivated-platelets  decoys  tumors  wyss-institute-at-harvard-university

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