Novel drug targets tumor growth in advanced kidney cancer

Harvard researchers at Dana-Farber Cancer Institute have developed a novel targeted drug that shows promise in advanced kidney cancer by interfering with the abnormal blood vessel formation that fuels tumor growth.

Richard Saltus
Feb. 12, 2020 | harvard

~4 mins   

Tags: health-medicine basic-research clear-cell-renal-cell-carcinoma dana-farber-cancer-institute hypoxia-inducible-factor kidney-cancer metastatic-disease mk-6482 nobel-prize phase-iii toni-choueiri tumors william-g-kaelin-jr

Exposing how pancreatic cancer does its dirty work

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell
Aug. 28, 2019 | harvard

~8 mins   

Tags: science-technology angiogenesis basic-research cancer-cells endothelial-cells engineering harvards-wyss-institute-for-biologically-inspired-engineering immune-cells organ-on-chip pancreatic-cancer tumors

Solution to pancreatic cancer puzzle is discovered

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell
Aug. 28, 2019 | harvard

~8 mins   

Tags: science-technology angiogenesis cancer-cells endothelial-cells harvards-wyss-institute-for-biologically-inspired-engineering immune-cells organ-on-chip pancreatic-cancer tumors

Platelet ‘decoys’ outsmart both clots and cancer

A team of researchers at the Wyss Institute at Harvard University and several collaborating institutions has created a drug-free, reversible antiplatelet therapy that uses deactivated “decoy” platelets to reduce the risk of blood clots and potentially prevent cancer metastasis.

Lindsay Brownell
Feb. 13, 2019 | harvard

~8 mins   

Tags: health-medicine activated-platelets antiplatelet-drugs blood-clots deactivated-platelets decoys tumors wyss-institute-at-harvard-university

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