Human body-on-chip platform may speed up drug development

Multiple human organ chips that quantitatively predict drug pharmacokinetics may offer alternatives to some animal tests.

Benjamin Boettner | Jan. 27, 2020 | harvard
~15 mins   

Tags: science-technology drug-predictions engineering human-body-on-chip organ-chip science wyss-institute-for-biologically-inspired-engineering

Solid vaccine eliminates acute myeloid leukemia in mice

A new study presents an alternative treatment for acute myeloid leukemia (AML) that has the potential to eliminate AML cells completely.

Lindsay Brownell | Jan. 14, 2020 | harvard
~10 mins   

Tags: health-medicine acute-myeloid-leukemia-aml aml basic-research biomaterial-based-vaccine harvards-wyss-institute-for-biologically-inspired-engineering john-a-paulson-school-of-engineering-and-applied-sciences

A probiotic therapy for patients with inflammatory bowel disease

A genetically programmed living hydrogel material that facilitates intestinal wound healing is being considered for development as a probiotic therapy for patients with inflammatory bowel disease.

Benjamin Boettner | Dec. 6, 2019 | harvard
~7 mins   

Tags: science-technology basic-research crohns-disease e-wyss-institute-for-biologically-inspired-engineering-at-harvard e-coli-nissle-strain ibd inflammatory-bowel-disease mucosal-healing probiotic probiotic-therapy ulcerative-colitis

Better delivery system for sending chemo to cancerous lung tissue

A new technique called ELeCt (erythrocyte-leveraged chemotherapy) can transport drug-loaded nanoparticles into cancerous lung tissue by mounting them on the body’s own red blood cells.

Lindsay Brownell | Nov. 13, 2019 | harvard
~8 mins   

Tags: science-technology basic-research biodegradable-polymer cancer chemotherapy elect engineering erythrocyte-leveraged-chemotherapy john-a-paulson-school-of-engineering-and-applied-sciences lung-cancer trojan-horse wyss-institute-for-biologically-inspired-engineering


New blood test could be used to help millions infected with TB

A team of researchers has developed a point-of-care TB test that costs only $2 and gives results in about 30 minutes, lowering the barrier to care in low-resource settings and potentially saving millions of lives.

Lindsay Brownell | Oct. 23, 2019 | harvard
~9 mins   

Tags: health-medicine active-tuberculosis atb brigham-and-womens-hospital broad-institute-of-harvard-and-mit tb tb-triage-test wyss-institute-for-biologically-inspired-engineering

New technique being developed to therapeutically repair and replace human organs

A new technique called SWIFT (sacrificial writing into functional tissue) ultimately may be used therapeutically to repair and replace human organs with lab-grown versions containing patients’ own cells.

Lindsay Brownell | Sept. 6, 2019 | harvard
~7 mins   

Tags: science-technology 3d-printing adult-induced-pluripotent-stem-cells artificially-grown-human-organs harvard-john-a-paulson-school-of-engineering-and-applied-sciences harvards-wyss-institute-for-biologically-inspired-engineering organ-transplant sacrificial-writing-into-functional-tissue seas stem-cells swift

Exposing how pancreatic cancer does its dirty work

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell | Aug. 28, 2019 | harvard
~8 mins   

Tags: science-technology angiogenesis basic-research cancer-cells endothelial-cells engineering harvards-wyss-institute-for-biologically-inspired-engineering immune-cells organ-on-chip pancreatic-cancer tumors

Solution to pancreatic cancer puzzle is discovered

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell | Aug. 28, 2019 | harvard
~8 mins   

Tags: science-technology angiogenesis cancer-cells endothelial-cells harvards-wyss-institute-for-biologically-inspired-engineering immune-cells organ-on-chip pancreatic-cancer tumors

Ultra-soft underwater grippers reach next level of perfection

To study jellyfish and other fragile marine life without damaging them, researchers developed ultra-soft underwater grippers that catch and release jellyfish without harm.

Lindsay Brownell | Aug. 28, 2019 | harvard
~8 mins   

Tags: science-technology anti-aging baruch-college cuny harvard-john-a-paulson-school-of-engineering-and-applied-sciences harvards-wyss-institute-for-biologically-inspired-engineering jellyfish nina-sinatra seas wyss-institutes-bioinspired-soft-robotics-platform

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