Never-before-seen bacterium found at Arnold Arboretum

A new species of bacteria, one that makes its home on the relatively hot and dry surface of a solar panel, was discovered recently at the Arnold Arboretum, offering a lesson that nature’s reach extends even to the artificial.

Alvin Powell • harvard
Aug. 3, 2020 ~6 min

Tags: science-technology biodiversity bacteria basic-research michael-dosmann william-friedman arnold-arboretum alvin-powell wyss-institute-for-biologically-inspired-engineering environmental new-species kathryn-richardson kristie-tanner real-colegio-complutense solar-panel sphingomonas-solaris

Treatment significantly reduces symptoms of psoriasis in mice

Researchers have created a treatment that when applied directly to the skin in a mouse model of psoriasis, significantly reduces levels of inflammation and symptoms of psoriasis without systemic side effects.

Lindsay Brownell • harvard
July 22, 2020 ~9 min

Tags: science-technology john-a-paulson-school-of-engineering-and-applied-sciences wyss-institute-for-biologically-inspired-engineering steroids psoriasis ionic-liquid

Harvard scientists work to find coronavirus treatment

As the pandemic intensifies, Harvard scientists work to find a treatment.

Juan Siliezar • harvard
March 30, 2020 ~14 min

Tags:  covid-19  coronavirus  harvard-medical-school  health-medicine  brigham-and-womens-hospital  harvard-th-chan-school-of-public-health  massachusetts-general-hospital  george-church  wyss-institute-for-biologically-inspired-engineering  mark-namchuk  sarah-fortune  christoph-gorgulla  drug-repurposing-hub-of-the-broad-institute-of-mit-and-harvard  francisco-marty  haribabu-arthanari  jonathan-abraham  libby-hohmann  massachusetts-consortium-on-pathogen-readiness  remdesivir

Human body-on-chip platform may speed up drug development

Multiple human organ chips that quantitatively predict drug pharmacokinetics may offer alternatives to some animal tests.

Benjamin Boettner • harvard
Jan. 27, 2020 ~15 min

Tags:  science-technology  engineering  science  wyss-institute-for-biologically-inspired-engineering  drug-predictions  human-body-on-chip  organ-chip

Better delivery system for sending chemo to cancerous lung tissue

A new technique called ELeCt (erythrocyte-leveraged chemotherapy) can transport drug-loaded nanoparticles into cancerous lung tissue by mounting them on the body’s own red blood cells.

Lindsay Brownell • harvard
Nov. 13, 2019 ~8 min

Tags:  science-technology  engineering  cancer  basic-research  chemotherapy  john-a-paulson-school-of-engineering-and-applied-sciences  wyss-institute-for-biologically-inspired-engineering  lung-cancer  biodegradable-polymer  elect  erythrocyte-leveraged-chemotherapy  trojan-horse

New blood test could be used to help millions infected with TB

A team of researchers has developed a point-of-care TB test that costs only $2 and gives results in about 30 minutes, lowering the barrier to care in low-resource settings and potentially saving millions of lives.

Lindsay Brownell • harvard
Oct. 23, 2019 ~9 min

Tags:  health-medicine  brigham-and-womens-hospital  tb  wyss-institute-for-biologically-inspired-engineering  active-tuberculosis  atb  broad-institute-of-harvard-and-mit  tb-triage-test

Robobee makes its first solo flight

Several decades in the making, the Harvard Microbiotics Lab’s Robobee made its first solo flight.

Leah Burrows • harvard
June 26, 2019 ~6 min

Tags:  science-technology  harvard-john-a-paulson-school-of-engineering-and-applied-sciences  graduate-school-of-arts-and-sciences  seas  harvard-microrobotics-lab  robert-wood  robobee  wyss-institute-for-biologically-inspired-engineering

Performance-enhancing bacteria found in the human microbiome

A single microbe accumulating in the microbiome of elite athletes can enhance exercise performance in mice, paving the way to highly validated performance-enhancing probiotics.

Benjamin Boettner • harvard
June 24, 2019 ~9 min

Tags:  harvard-medical-school  health-medicine  george-church  wyss-institute-for-biologically-inspired-engineering  propionate  aleksandar-kostic  athletes  boston-marathon  jacob-luber  jonathan-scheiman  joslin-diabetes-center-in-boston  lactate  performance-enhancing-bacteria  probiotics  theodore-chavkin  v-atypica  veillonella

Engineered miniature kidneys come of age

By exposing stem cell-derived kidney organoids to fluidic shear stress, A team of Harvard researchers has significantly expanded the organoids’ vascular networks and improved the maturation of kidney compartments.

Benjamin Boettner • harvard
Feb. 11, 2019 ~6 min

Tags:  bioengineering  harvard-john-a-paulson-school-of-engineering-and-applied-sciences  health-medicine  brigham-and-womens-hospital  harvard-stem-cell-institute  organoids  wyss-institute-for-biologically-inspired-engineering  3d-organ-engineering  jennifer-lewis  joseph-bonventre  kidneys  kimberly-homan  navin-gupta  organs-in-a-dish  ryuji-morizane  vascularized-organoids  vasculature

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