Study finds path for addressing Alzheimer’s blood-brain barrier impairment

MIT researchers pinpoint mechanism and demonstrate that drugs could help.

David Orenstein | Picower Institute for Learning and Memory • mit
June 15, 2020 ~7 min

Tags: stem-cells medicine neuroscience alzheimers tissue-engineering research drug-development school-of-science brain-and-cognitive-sciences picower-institute

Study finds that aging neurons accumulate DNA damage

Reactivating an enzyme that promotes DNA repair can help to reverse age-related cognitive decline in mice.

Anne Trafton | MIT News Office • mit
May 18, 2020 ~5 min

Tags: neuroscience alzheimers aging research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih picower-institute

Alzheimer’s plaque emerges early and deep in the brain

Clumps of amyloid protein emerge early in deep regions, such as the mammillary body, and march outward in the brain along specific circuits.

David Orenstein | Picower Institute • mit
Oct. 8, 2019 ~6 min

Tags: neuroscience mental-health alzheimers disease research school-of-engineering school-of-science brain-and-cognitive-sciences institute-for-medical-engineering-and-science-imes picower-institute-for-learning-and-memory

Tissue model reveals role of blood-brain barrier in Alzheimer’s

Study finds that Alzheimer’s damage allows toxins to enter the brain, further harming neurons.

Anne Trafton | MIT News Office • mit
Aug. 12, 2019 ~6 min

Tags: medicine alzheimers disease research mechanical-engineering school-of-engineering biological-engineering health-sciences-and-technology



Why visual stimulation may work against Alzheimer’s

New findings help explain the surprising discovery that exposure to flickering light reduces amyloid plaques in mice.

Anne Trafton | MIT News Office • mit
May 7, 2019 ~7 min

Tags: neuroscience alzheimers research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih picower-institute


Brain wave stimulation may improve Alzheimer’s symptoms

Noninvasive treatment improves memory and reduces amyloid plaques in mice.

Anne Trafton | MIT News Office • mit
March 14, 2019 ~6 min

Tags: neuroscience memory alzheimers learning research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih picower-institute

Neuroscientists discover roles of gene linked to Alzheimer’s | MIT News

Study reveals why people with the APOE4 gene have higher risk of the disease.

Anne Trafton | MIT News Office • mit
May 31, 2018 ~7 min

Tags:  medicine  genetics  crispr  neuroscience  alzheimers  disease  research  school-of-science  brain-and-cognitive-sciences  national-institutes-of-health-nih  picower-institute

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