Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.

Professor Ernest Fraenkel has decoded fundamental aspects of Huntington’s disease and glioblastoma, and is now using computation to better understand amyotrophic lateral sclerosis.

A machine-learning method finds patterns of health decline in ALS, informing future clinical trial designs and mechanism discovery. The technique also extends to Alzheimer’s and Parkinson’s.

How 3D-printed models of neuronal axons could accelerate development of new therapies to treat neurodegenerative disorders.

Researchers have designed a skin-like device that can measure small facial movements in patients who have lost the ability to speak.