Mapping the brain’s sensory gatekeeper

New analysis could help uncover potential drug targets for attention deficits and sensory hypersensitivity.

Anne Trafton | MIT News Office • mit
July 22, 2020 ~7 min

Tags: neuroscience mental-health autism broad-institute research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute

Findings weaken notion that size equals strength for neural connections

Among study’s many surprises may be a new way to address Fragile X syndrome — by finding a “protein X.”

David Orenstein | Picower Institute for Learning and Memory • mit
July 14, 2020 ~5 min

Tags: neuroscience autism research school-of-science brain-and-cognitive-sciences synapses picower-institute

Scientists find a new way to reverse symptoms of Fragile X

Drug compound, tested in mice, could be effective in treating the leading heritable cause of intellectual disability and autism.

Anne Trafton | MIT News Office • mit
May 20, 2020 ~8 min

Tags: medicine autism broad-institute research school-of-science brain-and-cognitive-sciences picower-institute

The neural basis of sensory hypersensitivity

A new study may explain why people with autism are often highly sensitive to light and noise.

Anne Trafton | MIT News Office • mit
March 2, 2020 ~6 min

Tags: neuroscience autism research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute

Study may explain how infections reduce autism symptoms

An immune molecule sometimes produced during infection can influence the social behavior of mice.

Anne Trafton | MIT News Office • mit
Dec. 18, 2019 ~8 min

Tags: autism research school-of-science brain-and-cognitive-sciences national-science-foundation-nsf picower-institute

Drug combination reverses hypersensitivity to noise

Findings in mice suggest targeting certain brain circuits could offer new ways to treat some neurological disorders.

Anne Trafton | MIT News Office • mit
Oct. 21, 2019 ~7 min

Tags: neuroscience autism research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute

Neuroscientists identify brain region linked to altered social interactions in autism model

In a mouse model, restoring activity of a specific forebrain region reverses social traits associated with autism.

Sabbi Lall | McGovern Institute for Brain Research • mit
July 26, 2019 ~4 min

Tags: genetics neuroscience autism broad-institute research school-of-science brain-and-cognitive-sciences mcgovern-institute

Using gene editing, neuroscientists develop a new model for autism

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.

Anne Trafton | MIT News Office • mit
June 12, 2019 ~9 min

Tags: crispr neuroscience autism china broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences mcgovern-institute genome-editing

How we tune out distractions

Neuroscientists trace a brain circuit that filters unwanted sensory input.

Anne Trafton • mit
June 12, 2019 ~7 min

Tags: neuroscience autism research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih

Neuroscientists reverse some behavioral symptoms of Williams Syndrome

Mouse study yields insights into the rare condition, may shed light on other neurological disorders.

Anne Trafton | MIT News Office • mit
April 22, 2019 ~8 min

Tags: neuroscience autism research behavior school-of-science brain-and-cognitive-sciences mcgovern-institute

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