Rapid test for Covid-19 shows improved sensitivity

A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic.

Anne Trafton | MIT News Office • mit
Sept. 17, 2020 ~5 min

Tags: medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute

Mapping the brain’s sensory gatekeeper

New analysis could help uncover potential drug targets for attention deficits and sensory hypersensitivity.

Anne Trafton | MIT News Office • mit
July 22, 2020 ~7 min

Tags: neuroscience mental-health autism broad-institute research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute

Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA

Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.

David Orenstein | Picower Institute for Learning and Memory • mit
July 21, 2020 ~7 min

Tags: neuroscience rna immunology broad-institute research cells school-of-science brain-and-cognitive-sciences computer-science-and-artificial-intelligence-laboratory-csail picower-institute huntingtons

Engineers use “DNA origami” to identify vaccine design rules

In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.

Anne Trafton | MIT News Office • mit
June 29, 2020 ~7 min

Tags: covid-19 broad-institute ragon-institute vaccines research school-of-engineering national-institutes-of-health-nih materials-science-and-engineering dmse biological-engineering koch-institute

Research highlights immune molecule’s complex role in Huntington’s disease

Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes.

David Orenstein | Picower Institute for Learning and Memory • mit
June 8, 2020 ~4 min

Tags: neuroscience immunology broad-institute disease research school-of-science brain-and-cognitive-sciences picower-institute

Scientists find a new way to reverse symptoms of Fragile X

Drug compound, tested in mice, could be effective in treating the leading heritable cause of intellectual disability and autism.

Anne Trafton | MIT News Office • mit
May 20, 2020 ~8 min

Tags: medicine autism broad-institute research school-of-science brain-and-cognitive-sciences picower-institute

SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection

New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.

Sabbi Lall | McGovern Institute for Brain Research • mit
May 5, 2020 ~8 min

Tags: dna medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-science brain-and-cognitive-sciences health-science-and-technology

Researchers identify cells likely targeted by Covid-19 virus

Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection.

Anne Trafton | MIT News Office • mit
April 22, 2020 ~9 min

Tags: chemistry covid-19 broad-institute ragon-institute disease viruses research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes

Historic migration patterns are written in Americans' DNA

Genetic, geographic, and demographic data from more than 30,000 Americans reveal more genetic diversity within ancestry groups than previously thought.

Tom Ulrich | Broad Institute • mit
March 5, 2020 ~4 min

Tags: dna genetics broad-institute research school-of-architecture-and-planning school-of-engineering urban-studies-and-planning electrical-engineering-computer-science-eecs


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