The new front against antibiotic resistance

Deborah Hung shares research strategies to combat tuberculosis as part of the Department of Biology's IAP seminar series on microbes in health and disease.

Lucy Jakub | Department of Biology | Jan. 23, 2020 | mit
~6 mins   

Tags: biology broad-institute independent-activities-period school-of-science bacteria data microbes research antibiotics drug-development disease special-events-and-guest-speakers

Taking a moonshot at a rare childhood cancer

Team of researchers including MIT Professor Angela Koehler obtains $5.8 million grant to study fusion-positive alveolar rhabdomyosarcoma.

Bendta Schroeder | Koch Institute | Nov. 20, 2019 | mit
~6 mins   

Tags: koch-institute broad-institute biological-engineering school-of-engineering cancer medicine grants research national-institutes-of-health-nih funding biology

Biological engineer Paul Blainey creates new tools to advance biomedical research

His technology platforms have benefited genomics, diagnostics, and drug screening.

Anne Trafton | MIT News Office | Oct. 19, 2019 | mit
~8 mins   

Tags: research biological-engineering faculty broad-institute school-of-engineering profile imaging microfluidics genetics drug-development

Technique can image individual proteins within synapses

Rapid imaging method could help reveal how conditions such as autism affect brain cells.

Anne Trafton | MIT News Office | Sept. 26, 2019 | mit
~7 mins   

Tags: research biological-engineering broad-institute school-of-engineering neuroscience dna synapses imaging national-institutes-of-health-nih national-science-foundation-nsf

A comprehensive catalogue of human digestive tract bacteria

Researchers identify nearly 8,000 strains of bacteria, while also clarifying their genetic and metabolic context.

Anne Trafton | MIT News Office | Sept. 2, 2019 | mit
~7 mins   

Tags: research biological-engineering civil-and-environmental-engineering microbes basteria health genetics broad-institute school-of-engineering

Neuroscientists identify brain region linked to altered social interactions in autism model

In a mouse model, restoring activity of a specific forebrain region reverses social traits associated with autism.

Sabbi Lall | McGovern Institute for Brain Research | July 26, 2019 | mit
~4 mins   

Tags: mcgovern-institute broad-institute brain-and-cognitive-sciences school-of-science autism genetics research neuroscience

New CRISPR platform expands RNA editing capabilities

The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.

Sabbi Lall | McGovern Institute for Brain Research | July 11, 2019 | mit
~6 mins   

Tags: mcgovern-institute broad-institute brain-and-cognitive-sciences biological-engineering school-of-science crispr school-of-engineering rna dna genetics research

A chemical approach to imaging cells from the inside

Researchers develop a new microscopy system for creating maps of cells, using chemical reactions to encode spatial information.

Karen Zusi | Broad Institute | June 20, 2019 | mit
~4 mins   

Tags: research rna dna broad-institute biological-engineering brain-and-cognitive-sciences mcgovern-institute school-of-science school-of-engineering imaging microscopy

Using gene editing, neuroscientists develop a new model for autism

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.

Anne Trafton | MIT News Office | June 12, 2019 | mit
~9 mins   

Tags: research autism crispr genome-editing brain-and-cognitive-sciences neuroscience mcgovern-institute broad-institute school-of-science school-of-engineering china

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.

Karen Zusi | Broad Institute | June 12, 2019 | mit
~7 mins   

Tags: research crispr genome-editing rna dna genetics broad-institute mcgovern-institute biological-engineering brain-and-cognitive-sciences school-of-science school-of-engineering

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