Using this computational system, researchers can identify viral protein sequences that could make better vaccine targets.
Jan. 14, 2021 • ~8 min
mathematics genetics artificial-intelligence covid-19 hivaids broad-institute microbes vaccines viruses research school-of-engineering school-of-science electrical-engineering-computer-science-eecs computer-science-and-technology computer-science-and-artificial-intelligence-laboratory-csail national-science-foundation-nsf biological-engineering mit-schwarzman-college-of-computing
A diverse group of researchers is working to turn new discoveries about the trillions of microbes in the body into treatments for a range of diseases.
Jan. 5, 2021 • ~10 min
health medicine bacteria startups broad-institute microbes disease research drug-development school-of-engineering innovation-and-entrepreneurship-ie alumniae biological-engineering
Computational method for screening drug compounds can help predict which ones will work best against tuberculosis or other diseases.
Oct. 15, 2020 • ~7 min
machine-learning mathematics medicine drug-discovery artificial-intelligence broad-institute research school-of-engineering school-of-science electrical-engineering-computer-science-eecs computer-science-and-artificial-intelligence-laboratory-csail biological-engineering mit-schwarzman-college-of-computing
Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.
Oct. 13, 2020 • ~7 min
chemistry broad-institute ragon-institute research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes
A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic.
Sept. 17, 2020 • ~5 min
medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute
New analysis could help uncover potential drug targets for attention deficits and sensory hypersensitivity.
July 22, 2020 • ~7 min
neuroscience mental-health autism broad-institute research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute
Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.
July 21, 2020 • ~7 min
neuroscience rna immunology broad-institute research cells school-of-science brain-and-cognitive-sciences computer-science-and-artificial-intelligence-laboratory-csail picower-institute huntingtons
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
June 29, 2020 • ~7 min
covid-19 broad-institute ragon-institute vaccines research school-of-engineering national-institutes-of-health-nih materials-science-and-engineering dmse biological-engineering koch-institute
Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes.
June 8, 2020 • ~4 min
neuroscience immunology broad-institute disease research school-of-science brain-and-cognitive-sciences picower-institute
Drug compound, tested in mice, could be effective in treating the leading heritable cause of intellectual disability and autism.
May 20, 2020 • ~8 min
medicine autism broad-institute research school-of-science brain-and-cognitive-sciences picower-institute