Catching cancer in the act

Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.

Eva Frederick | Whitehead Institute • mit
Jan. 22, 2021 ~10 min

Regulating the regulators

Tiny microRNAs help destroy unwanted messenger RNAs in cells. New research finds how the body keeps them in check.

Eva Frederick | Whitehead Institute • mit
Nov. 24, 2020 ~6 min

Rapid test for Covid-19 shows improved sensitivity

A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic.

Anne Trafton | MIT News Office • mit
Sept. 17, 2020 ~5 min

Nature-inspired CRISPR enzymes for expansive genome editing

Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

Media Lab • mit
May 19, 2020 ~6 min

SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection

New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.

Sabbi Lall | McGovern Institute for Brain Research • mit
May 5, 2020 ~8 min

Genetic screen offers new drug targets for Huntington’s disease

Neuroscientists identify genes that modulate the disease’s toxic effects.

Anne Trafton | MIT News Office • mit
Jan. 30, 2020 ~8 min

Putting a finger on the switch of chronic parasite infection

Researchers find master regulator needed for Toxoplasma gondii parasite to chronically infect host; promising step toward infection treatment, prevention.

Greta Friar | Whitehead Institute • mit
Jan. 21, 2020 ~6 min

Using CRISPR to program gels with new functions

Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.

Anne Trafton | MIT News Office • mit
Aug. 22, 2019 ~6 min

High-precision technique stores cellular “memory” in DNA

Engineers program human and bacterial cells to keep a record of complex molecular events.

Anne Trafton | MIT News Office • mit
Aug. 22, 2019 ~7 min

Speeding up drug discovery for brain diseases

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.

Nicole Davis • mit
July 31, 2019 ~6 min

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