Rapid test for Covid-19 shows improved sensitivity

A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic.

Anne Trafton | MIT News Office • mit
Sept. 17, 2020 ~5 min

Tags: medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute

Nature-inspired CRISPR enzymes for expansive genome editing

Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

Media Lab • mit
May 19, 2020 ~6 min

Tags: dna crispr covid-19 rna research computational-biology media-lab school-of-architecture-and-planning alumniae genome-editing center-for-bits-and-atoms

SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection

New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.

Sabbi Lall | McGovern Institute for Brain Research • mit
May 5, 2020 ~8 min

Tags: dna medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-science brain-and-cognitive-sciences health-science-and-technology


Putting a finger on the switch of chronic parasite infection

Researchers find master regulator needed for Toxoplasma gondii parasite to chronically infect host; promising step toward infection treatment, prevention.

Greta Friar | Whitehead Institute • mit
Jan. 21, 2020 ~6 min

Tags: chemistry medicine genetics crispr biology disease research school-of-science whitehead-institute parasites

Using CRISPR to program gels with new functions

Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.

Anne Trafton | MIT News Office • mit
Aug. 22, 2019 ~6 min

Tags: dna genetics crispr research school-of-engineering biological-engineering institute-for-medical-engineering-and-science-imes drug-delivery diagnostic-devices


Speeding up drug discovery for brain diseases

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.

Nicole Davis • mit
July 31, 2019 ~6 min

Tags: genetics crispr mental-health development biology pharmaceuticals disease research drug-development behavior proteins school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih whitehead-institute picower-institute

New CRISPR platform expands RNA editing capabilities

The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.

Sabbi Lall | McGovern Institute for Brain Research • mit
July 11, 2019 ~6 min

Tags: dna genetics crispr rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute

Using gene editing, neuroscientists develop a new model for autism

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.

Anne Trafton | MIT News Office • mit
June 12, 2019 ~9 min

Tags: crispr neuroscience autism china broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences mcgovern-institute genome-editing

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