Scientists discover new rules about “runaway” transcription

Findings related to bacterial gene expression overturn fundamental assumptions about basic biological pathways.

Raleigh McElvery | Department of Biology • mit
Sept. 2, 2020 ~7 min

Tags: dna physics genetics bacteria biology rna research school-of-science

Gene-controlling mechanisms play key role in cancer progression

Study finds “epigenomic” alterations evolve as lung tumors become more aggressive and metastasize.

Anne Trafton | MIT News Office • mit
July 23, 2020 ~7 min

Tags: dna cancer biology research school-of-science national-institutes-of-health-nih koch-institute

3 Questions: Ibrahim Cissé on using physics to decipher biology

A biophysicist employs super-resolution microscopy to peer inside living cells and witness never-before-seen phenomena.

Raleigh McElvery | Department of Biology • mit
July 22, 2020 ~7 min

Tags: dna physics biology research school-of-science faculty 3-questions

Nature-inspired CRISPR enzymes for expansive genome editing

Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

Media Lab • mit
May 19, 2020 ~6 min

Tags: dna crispr covid-19 rna research computational-biology media-lab school-of-architecture-and-planning alumniae genome-editing center-for-bits-and-atoms

SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection

New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.

Sabbi Lall | McGovern Institute for Brain Research • mit
May 5, 2020 ~8 min

Tags: dna medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-science brain-and-cognitive-sciences health-science-and-technology

Newly discovered enzyme “square dance” helps generate DNA building blocks

MIT biochemists can trap and visualize an enzyme as it becomes active — an important development that may aid in future drug development.

Raleigh McElvery | Department of Biology • mit
March 30, 2020 ~5 min

Tags: dna chemistry health energy biology disease research biochemistry school-of-science

Historic migration patterns are written in Americans' DNA

Genetic, geographic, and demographic data from more than 30,000 Americans reveal more genetic diversity within ancestry groups than previously thought.

Tom Ulrich | Broad Institute • mit
March 5, 2020 ~4 min

Tags: dna genetics broad-institute research school-of-architecture-and-planning school-of-engineering urban-studies-and-planning electrical-engineering-computer-science-eecs

Screen could offer better safety tests for new chemicals

Using specialized liver cells, a new test can quickly detect potentially cancer-causing DNA damage.

Anne Trafton | MIT News Office • mit
Dec. 17, 2019 ~7 min

Tags: dna environment cancer research drug-development school-of-engineering national-institutes-of-health-nih biological-engineering health-sciences-and-technology

A new way to regulate gene expression

Biologists uncover an evolutionary trick to control gene expression that reverses the flow of genetic information from RNA splicing back to transcription.

Raleigh McElvery | Department of Biology • mit
Dec. 9, 2019 ~6 min

Tags: dna evolution health genetics biology data disease research school-of-science national-institutes-of-health-nih

How biomarkers can record and reconstruct climate trends

Scientists reveal the genes and proteins controlling the chemical structure of a paleoclimate biomarker.

Fatima Husain | EAPS • mit
Dec. 4, 2019 ~5 min

Tags: dna evolution genetics geology climate-change climate bacteria biology microbes research school-of-science national-science-foundation-nsf eaps department-of-energy-doe ocean-science earth-and-atmospheric-sciences

Page 1 of 9