Catching cancer in the act

Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.

Eva Frederick | Whitehead Institute • mit
today ~10 min

dna genetics crispr cancer biology research cells school-of-science national-institutes-of-health-nih whitehead-institute

Why cancer cells waste so much energy

MIT study sheds light on the longstanding question of why cancer cells get their energy from fermentation.

Anne Trafton | MIT News Office • mit
Jan. 15, 2021 ~6 min

dna cancer biology research cells school-of-science national-science-foundation-nsf national-institutes-of-health-nih koch-institute

Neuroscientists discover a molecular mechanism that allows memories to form

Modifications to chromosomes in “engram” neurons control the encoding and retrieval of memories.

Anne Trafton | MIT News Office • mit
Oct. 5, 2020 ~7 min

dna genetics neuroscience memory research school-of-science brain-and-cognitive-sciences picower-institute

Scientists discover new rules about “runaway” transcription

Findings related to bacterial gene expression overturn fundamental assumptions about basic biological pathways.

Raleigh McElvery | Department of Biology • mit
Sept. 2, 2020 ~7 min

dna physics genetics bacteria biology rna research school-of-science

Gene-controlling mechanisms play key role in cancer progression

Study finds “epigenomic” alterations evolve as lung tumors become more aggressive and metastasize.

Anne Trafton | MIT News Office • mit
July 23, 2020 ~7 min

dna cancer biology research school-of-science national-institutes-of-health-nih koch-institute

3 Questions: Ibrahim Cissé on using physics to decipher biology

A biophysicist employs super-resolution microscopy to peer inside living cells and witness never-before-seen phenomena.

Raleigh McElvery | Department of Biology • mit
July 22, 2020 ~7 min

dna physics biology research school-of-science faculty 3-questions

Nature-inspired CRISPR enzymes for expansive genome editing

Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

Media Lab • mit
May 19, 2020 ~6 min

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SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection

New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.

Sabbi Lall | McGovern Institute for Brain Research • mit
May 5, 2020 ~8 min

dna medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-science brain-and-cognitive-sciences health-science-and-technology

Newly discovered enzyme “square dance” helps generate DNA building blocks

MIT biochemists can trap and visualize an enzyme as it becomes active — an important development that may aid in future drug development.

Raleigh McElvery | Department of Biology • mit
March 30, 2020 ~5 min

dna chemistry health energy biology disease research biochemistry school-of-science

Historic migration patterns are written in Americans' DNA

Genetic, geographic, and demographic data from more than 30,000 Americans reveal more genetic diversity within ancestry groups than previously thought.

Tom Ulrich | Broad Institute • mit
March 5, 2020 ~4 min

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