3 Questions: Mriganka Sur on researching the first approved drug to treat Rett syndrome

On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1. The MIT professor's original research showing that IGF-1 could treat Rett was published in 2009.

David Orenstein | Picower Institute for Learning and Memory • mit
March 13, 2023 ~9 min

New purification method could make protein drugs cheaper

MIT engineers find specialized nanoparticles can quickly and inexpensively isolate proteins from a bioreactor.

Anne Trafton | MIT News Office • mit
Feb. 28, 2023 ~7 min


A new educational program for scientists working on substance use disorder

MIT Open Learning team awarded NIH grant to provide training in biomedical product development, entrepreneurship, and innovation.

MIT Open Learning • mit
Feb. 8, 2023 ~7 min

Artificial intelligence model can detect Parkinson’s from breathing patterns

An MIT-developed device with the appearance of a Wi-Fi router uses a neural network to discern the presence and severity of one of the fastest-growing neurological diseases in the world.

Alex Ouyang | Abdul Latif Jameel Clinic for Machine Learning in Health • mit
Aug. 22, 2022 ~6 min

Artificial intelligence model finds potential drug molecules a thousand times faster

A geometric deep-learning model is faster and more accurate than state-of-the-art computational models, reducing the chances and costs of drug trial failures.

Alex Ouyang | Abdul Latif Jameel Clinic for Machine Learning in Health • mit
July 12, 2022 ~6 min

A smarter way to develop new drugs

A new artificial intelligence technique only proposes candidate molecules that can actually be produced in a lab.

Adam Zewe | MIT News Office • mit
April 26, 2022 ~8 min

An “oracle” for predicting the evolution of gene regulation

Researchers create a mathematical framework to examine the genome and detect signatures of natural selection, deciphering the evolutionary past and future of non-coding DNA.

Raleigh McElvery | Department of Biology • mit
March 11, 2022 ~9 min

Chemical synthesis yields potential antibiotic

A new strategy for producing a natural compound could also be used to generate variants with even stronger antimicrobial activity.

Anne Trafton | MIT News Office • mit
Feb. 24, 2022 ~6 min


Measuring cancer cell state can reveal drug susceptibility

Study results also show that pancreatic tumor cells can be forced into a more susceptible state by changing their environment.

Anne Trafton | MIT News Office • mit
Dec. 9, 2021 ~8 min

Taking some of the guesswork out of drug discovery

A deep learning model rapidly predicts the 3D shapes of drug-like molecules, which could accelerate the process of discovering new medicines.

Adam Zewe | MIT News Office • mit
Dec. 6, 2021 ~7 min

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