Technique recovers lost single-cell RNA-sequencing information

Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.

Anne Trafton | MIT News Office • mit
Oct. 13, 2020 ~7 min

Tags: chemistry broad-institute ragon-institute research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes

Nanoparticles can turn off genes in bone marrow cells

Using these new particles, researchers could develop treatments for heart disease and other conditions.

Anne Trafton | MIT News Office • mit
Oct. 5, 2020 ~8 min

Tags: genetics rna research school-of-engineering nanoscience-and-nanotechnology koch-institute institute-for-medical-engineering-and-science-imes chemical-engeering

Cancer researchers collaborate, target DNA damage repair pathways for cancer therapy

MIT researchers find blocking the expressions of the genes XPA and MK2 enhances the tumor-shrinking effects of platinum-based chemotherapies in p53-mutated cancers.

Koch Institute • mit
Oct. 1, 2020 ~7 min

Tags: chemistry medicine cancer research school-of-engineering school-of-science biological-engineering koch-institute chemical-engineering

Synthetic coating for the GI tract could deliver drugs or aid in digestion

MIT engineers devise a temporary film that may help treat diabetes, infections, and other conditions.

Anne Trafton | MIT News Office • mit
Aug. 26, 2020 ~6 min

Tags: health medicine research mechanical-engineering school-of-engineering national-institutes-of-health-nih koch-institute drug-delivery

Gene-controlling mechanisms play key role in cancer progression

Study finds “epigenomic” alterations evolve as lung tumors become more aggressive and metastasize.

Anne Trafton | MIT News Office • mit
July 23, 2020 ~7 min

Tags: dna cancer biology research school-of-science national-institutes-of-health-nih koch-institute

Exhaled biomarkers can reveal lung disease

Specialized nanoparticles create a “breath signal” that could be used to diagnose pneumonia and other infectious or genetic diseases.

Anne Trafton | MIT News Office • mit
July 20, 2020 ~5 min

Tags: medicine research sensors school-of-engineering harvard-mit-health-sciences-and-technology electrical-engineering-computer-science-eecs nanoscience-and-nanotechnology koch-institute health-sciences-and-technology lincoln-laboratory diagnostics

COMMANDing drug delivery

A new computational method fine-tunes delivery of therapeutics to specific brain regions.

Sabbi Lall | McGovern Institute for Brain Research • mit
July 10, 2020 ~6 min

Tags: medicine neuroscience research school-of-science brain-and-cognitive-sciences materials-science-and-engineering dmse koch-institute mcgovern-institute drug-delivery

Engineers design a reusable, silicone rubber face mask

The prototype mask, which includes an N95 filter, can be easily sterilized and worn many times.

Anne Trafton | MIT News Office • mit
July 9, 2020 ~7 min

Tags: medicine covid-19 pandemic research medical-devices mechanical-engineering school-of-engineering national-institutes-of-health-nih koch-institute health-sciences-and-technology

Helping drug-delivering particles squeeze through a syringe

MIT engineers are using computing modeling to prevent microparticles from clogging during injections.

Anne Trafton | MIT News Office • mit
July 8, 2020 ~6 min

Tags: research mechanical-engineering school-of-engineering koch-institute chemical-engineering drug-delivery

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