Nature-inspired CRISPR enzymes for expansive genome editing

Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

Media Lab • mit
May 19, 2020 ~6 min

Tags: dna crispr covid-19 rna research computational-biology media-lab school-of-architecture-and-planning alumniae genome-editing center-for-bits-and-atoms

SMART researchers receive grant to develop rapid tests for Covid-19

Using engineered binder proteins to detect viral proteins or antibodies rather than RNA, new tests may overcome current challenges in testing for SARS-CoV-2 virus.

Singapore-MIT Alliance for Research and Technology • mit
May 19, 2020 ~9 min

Tags: health public-health covid-19 pandemic rna disease research proteins school-of-engineering grants singapore-mit-alliance-for-research-and-technology-smart

HIV genome bends over backwards to help virus take over cells

Differently shaped RNA molecules allow HIV to express different genes from the same RNA sequence.

Eva Frederick | Whitehead Institute • mit
May 11, 2020 ~9 min

Tags: medicine genetics hivaids biology rna disease viruses research computer-science-and-technology algorithms whitehead-institute


Delivery system can make RNA vaccines more powerful

Vaccines packaged in novel nanoparticles could offer a new way to fight cancer and infectious diseases.

Anne Trafton | MIT News Office • mit
Sept. 30, 2019 ~5 min

Tags: cancer ebola rna vaccines disease research school-of-engineering koch-institute chemical-engineering institute-of-medical-engineering-and-science-imes

An emerging view of RNA transcription and splicing

Whitehead Institute scientists find chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression.

Nicole Davis | Whitehead Institute • mit
Aug. 9, 2019 ~6 min

Tags: dna genetics biology rna research school-of-science whitehead-institute

New CRISPR platform expands RNA editing capabilities

The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.

Sabbi Lall | McGovern Institute for Brain Research • mit
July 11, 2019 ~6 min

Tags: dna genetics crispr rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute

A chemical approach to imaging cells from the inside

Researchers develop a new microscopy system for creating maps of cells, using chemical reactions to encode spatial information.

Karen Zusi | Broad Institute • mit
June 20, 2019 ~4 min

Tags: dna imaging microscopy rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.

Karen Zusi | Broad Institute • mit
June 12, 2019 ~7 min

Tags: dna genetics crispr rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute genome-editing

Earliest life may have arisen in ponds, not oceans

Study finds shallow bodies of water were probably more suitable for Earth’s first life forms.

Jennifer Chu | MIT News Office • mit
April 12, 2019 ~5 min

Tags: evolution chemistry environment biology rna research school-of-science planetary-science eaps earth-and-atmospheric-sciences

Page 1 of 4