MIT-led team receives funding to pursue new treatments for metabolic disease

Awarded $65.67 million from ARPA-H, the researchers will work to develop ingestible capsules that deliver mRNA and electric stimuli to treat metabolic disorders such as diabetes.

Anne Trafton | MIT News • mit
Feb. 5, 2024 ~6 min

Noninvasive technique reveals how cells’ gene expression changes over time

MIT researchers can now track a cell’s RNA expression to investigate long-term processes like cancer progression or embryonic development.

Anne Trafton | MIT News • mit
Jan. 10, 2024 ~7 min


Nanoparticle-delivered RNA reduces neuroinflammation in lab tests

MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.

David Orenstein | Picower Institute • mit
Dec. 15, 2023 ~7 min

Search algorithm reveals nearly 200 new kinds of CRISPR systems

By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.

Allessandra DiCorato | Broad Institute • mit
Nov. 23, 2023 ~8 min

Thousands of programmable DNA-cutters found in algae, snails, and other organisms

New research finds RNA-guided enzymes called Fanzors are widespread among eukaryotic organisms.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Oct. 13, 2023 ~6 min

Individual neurons mix multiple RNA edits of key synapse protein, study finds

Neurons stochastically generated up to eight different versions of a protein-regulating neurotransmitter release, which could vary how they communicate with other cells.

David Orenstein | The Picower Institute for Learning and Memory • mit
Sept. 25, 2023 ~7 min

MIT engineers design more powerful RNA vaccines

The new approach could lead to intranasal vaccines for Covid-19 and other respiratory diseases.

Anne Trafton | MIT News • mit
Sept. 7, 2023 ~8 min

Study connects neural gene expression differences to functional distinctions

Researchers compared a pair of superficially similar motor neurons in fruit flies to examine how their differing use of the same genome produced distinctions in form and function.

David Orenstein | The Picower Institute for Learning and Memory • mit
Aug. 25, 2023 ~8 min


Study explains how part of the nucleolus evolved

A single protein can self-assemble to build the scaffold for a biomolecular condensate that makes up a key nucleolar compartment.

Anne Trafton | MIT News • mit
Aug. 15, 2023 ~7 min

Newly discovered bacterial communication system aids antimicrobial resistance

SMART researchers find the enzyne RlmN, which directly senses chemical and environmental stresses, can be targeted in drug development.

Singapore-MIT Alliance for Research and Technology • mit
Aug. 2, 2023 ~6 min

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