Whitehead Institute researchers find many transcription factors bind RNA, which fine-tunes their regulation of gene expression, suggesting new therapeutic opportunities.

A new technology called RIBOmap can give researchers valuable insight into how protein production in animal and human tissue is altered in disease.

The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.

Using this approach, researchers hope to deliver therapeutic RNA molecules selectively to cancer cells or other target cells.

Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue.

A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement.

“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.

Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.

Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.

MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme.