Engineers use “DNA origami” to identify vaccine design rules

In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.

Anne Trafton | MIT News Office • mit
June 29, 2020 ~7 min

Tags: covid-19 broad-institute ragon-institute vaccines research school-of-engineering national-institutes-of-health-nih materials-science-and-engineering dmse biological-engineering koch-institute

How often do vaccine trials hit paydirt?

Study: Vaccines find more success in development than any other kind of drug, but have been relatively neglected in recent decades.

Peter Dizikes | MIT News Office • mit
May 27, 2020 ~8 min

Tags: medicine public-health covid-19 industry pandemic policy health-care antibiotics vaccines research government drug-development innovation-and-entrepreneurship-ie sloan-school-of-management business-and-management

MIT’s Love Lab developing a Covid-19 vaccine to potentially reach billions

Manufacturability is key to producing a widely available, affordable vaccine.

Ashley Belanger | School of Engineering • mit
April 22, 2020 ~8 min

Tags: medicine covid-19 manufacturing pandemic health-care vaccines research school-of-engineering biological-engineering koch-institute chemical-engineering

Storing medical information below the skin’s surface

Specialized dye, delivered along with a vaccine, could enable “on-patient” storage of vaccination history.

Anne Trafton | MIT News Office • mit
Dec. 18, 2019 ~7 min

Tags: medicine quantum-dots vaccines research school-of-engineering developing-countries koch-institute chemical-engineering health-science-and-technology

Delivery system can make RNA vaccines more powerful

Vaccines packaged in novel nanoparticles could offer a new way to fight cancer and infectious diseases.

Anne Trafton | MIT News Office • mit
Sept. 30, 2019 ~5 min

Tags: cancer ebola rna vaccines disease research school-of-engineering koch-institute chemical-engineering institute-of-medical-engineering-and-science-imes


A single-injection vaccine for the polio virus | MIT News

Nanoparticles could offer a new way to help eradicate the disease worldwide.

Anne Trafton | MIT News Office • mit
May 21, 2018 ~6 min

Tags:  medicine  microbes  vaccines  disease  research  drug-development  school-of-engineering  developing-countries  nanoscience-and-nanotechnology  koch-institute  chemical-engineering  drug-delivery

Deploying therapeutic payloads to cells | MIT News

Mark Bathe develops molecular packages for targeted delivery of drugs, vaccines, and gene-editing tools.

Helen Knight | MIT News correspondent • mit
June 4, 2017 ~6 min

Tags:  dna  crispr  vaccines  research  school-of-engineering  alumniae  faculty  nanoscience-and-nanotechnology  biological-engineering  drug-delivery  bioengineering-and-biotechnology  profiles

Progress toward a Zika vaccine | MIT News

Researchers program RNA nanoparticles that could protect against the virus.

Anne Trafton | MIT News Office • mit
March 29, 2017 ~8 min

Tags:  medicine  cancer  rna  microbes  vaccines  disease  research  drug-development  school-of-engineering  whitehead-institute  koch-institute  chemical-engineering

MIT undertakes Grand Challenge for innovation in global vaccine manufacturing | MIT News

Bill and Melinda Gates Foundation awards MIT, University College London, and University of Kansas $17.6M for development and production of low-cost vaccines.

Koch Institute • mit
Feb. 22, 2017 ~6 min

Tags:  medicine  manufacturing  vaccines  research  drug-development  mechanical-engineering  school-of-engineering  koch-institute  chemical-engineering  grants

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