Whitehead Institute team resolves structure of master growth regulator

New research reveals how mTORC1 docks at lysosomal surface.

Nicole Davis | Whitehead Institute | Oct. 18, 2019 | mit
~6 mins   

Tags: whitehead-institute biology school-of-science national-institutes-of-health-nih research drug-discovery

Ruth Lehmann elected as director of Whitehead Institute

Lehmann, a world-renowned developmental and cell biology researcher, is the institute’s fifth director.

Lisa Girard | Whitehead Institute | Sept. 19, 2019 | mit
~9 mins   

Tags: whitehead-institute school-of-science biology research administration cells


An emerging view of RNA transcription and splicing

Whitehead Institute scientists find chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression.

Nicole Davis | Whitehead Institute | Aug. 9, 2019 | mit
~6 mins   

Tags: whitehead-institute biology school-of-science genetics research rna dna


Speeding up drug discovery for brain diseases

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.

Nicole Davis | July 31, 2019 | mit
~6 mins   

Tags: whitehead-institute picower-institute school-of-science behavior biology brain-and-cognitive-sciences crispr development disease genetics mental-health national-institutes-of-health-nih pharmaceuticals research proteins drug-development

Uncovering the riches of traditional global medicine

Researchers solve how the kava plant produces its pain-relieving and anti-anxiety molecules, demonstrate an extensible method to scale and optimize production.

Greta Friar | Whitehead Institute | July 23, 2019 | mit
~7 mins   

Tags: whitehead-institute biology school-of-science evolution genetics mental-health national-science-foundation-nsf research health plants

Genetic study takes research on sex differences to new heights

Differences in male and female gene expression, including those contributing to height differences, found throughout the body in humans and other mammals.

Greta Friar | Whitehead Institute | July 18, 2019 | mit
~8 mins   

Tags: whitehead-institute school-of-science biology evolution genetics national-institutes-of-health-nih research animals

Revising the textbook on introns

Whitehead Institute researchers uncover a group of introns in yeast that possess surprising stability and function.

Nicole Davis | Whitehead Institute | Jan. 16, 2019 | mit
~5 mins   

Tags: school-of-science biology whitehead-institute genetics national-institutes-of-health-nih research dna

Cracking a tough case

Whitehead Institute and MIT researchers uncover the detailed molecular structure of the sporopollenin polymer, an inert material key for the emergence of land plants.

Greta Friar | Whitehead Institute | Dec. 17, 2018 | mit
~7 mins   

Tags: school-of-science chemistry biology department-of-energy-doe evolution research whitehead-institute biochemistry plants

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