Blood cell family trees trace how production changes with aging

Whitehead Institute Member Jonathan Weissman and collaborators developed a tool to reconstruct human cell family trees, revealing how blood cell production changes in old age.

Greta Friar | Whitehead Institute • mit
Jan. 31, 2024 ~11 min

Simons Center’s collaborative approach propels autism research, at MIT and beyond

Team-based targeted projects, multi-mentor fellowships ensure that scientists studying social cognition, behavior, and autism integrate multiple perspectives and approaches to pressing questions.

David Orenstein | Simons Center for the Social Brain • mit
Jan. 30, 2024 ~12 min


It takes three to tango: transcription factors bind DNA, protein, and RNA

Whitehead Institute researchers find many transcription factors bind RNA, which fine-tunes their regulation of gene expression, suggesting new therapeutic opportunities.

Greta Friar | Whitehead Institute • mit
July 17, 2023 ~7 min

Focus on function helps identify the changes that made us human

A new approach for identifying significant differences in gene use between closely-related species provides insights into human evolution.

Greta Friar | Whitehead Institute • mit
July 6, 2023 ~11 min

Inaugural J-WAFS Grand Challenge aims to develop enhanced crop variants and move them from lab to land

Matt Shoulders will lead an interdisciplinary team to improve RuBisCO — the photosynthesis enzyme thought to be the holy grail for improving agricultural yield.

Carolyn Blais | Abdul Latif Jameel Water and Food Systems Lab • mit
May 10, 2023 ~14 min

3 Questions: Mriganka Sur on researching the first approved drug to treat Rett syndrome

On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1. The MIT professor's original research showing that IGF-1 could treat Rett was published in 2009.

David Orenstein | Picower Institute for Learning and Memory • mit
March 13, 2023 ~9 min

Scientists unveil the functional landscape of essential genes

Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.

Nicole Davis | Whitehead Institute • mit
Nov. 21, 2022 ~6 min

Genome-wide screens could reveal the liver’s secrets

A new technique for studying liver cells within an organism could shed light on the genes required for regeneration.

Anne Trafton | MIT News Office • mit
Nov. 15, 2022 ~8 min


A “door” into the mitochondrial membrane

Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.

Eva Frederick | Whitehead Institute • mit
Oct. 25, 2022 ~7 min

Four from MIT receive NIH New Innovator Awards for 2022

Awards support high-risk, high-impact research from early-career investigators.

Phie Jacobs | School of Science • mit
Oct. 4, 2022 ~5 min

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