Using CRISPR to program gels with new functions

Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.

Anne Trafton | MIT News Office | Aug. 22, 2019 | mit
~6 mins   

Tags: research dna crispr genetics diagnostic-devices drug-delivery biological-engineering institute-for-medical-engineering-and-science-imes school-of-engineering

An emerging view of RNA transcription and splicing

Whitehead Institute scientists find chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression.

Nicole Davis | Whitehead Institute | Aug. 9, 2019 | mit
~6 mins   

Tags: whitehead-institute biology school-of-science genetics research rna dna

A new way to block unwanted genetic transfer

Researchers identify a strategy to prevent mobile genetic elements from breaching the bacterial cell wall.

Raleigh McElvery | Department of Biology | Aug. 5, 2019 | mit
~9 mins   

Tags: biology school-of-science bacteria health microbes research national-institutes-of-health-nih dna genetics

New CRISPR platform expands RNA editing capabilities

The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.

Sabbi Lall | McGovern Institute for Brain Research | July 11, 2019 | mit
~6 mins   

Tags: mcgovern-institute broad-institute brain-and-cognitive-sciences biological-engineering school-of-science crispr school-of-engineering rna dna genetics research

A chemical approach to imaging cells from the inside

Researchers develop a new microscopy system for creating maps of cells, using chemical reactions to encode spatial information.

Karen Zusi | Broad Institute | June 20, 2019 | mit
~4 mins   

Tags: research rna dna broad-institute biological-engineering brain-and-cognitive-sciences mcgovern-institute school-of-science school-of-engineering imaging microscopy

How to detect life on Mars

Scientists from the Search for Extra-Terrestrial Genomes instrument team develop method to detect the tiniest traces of life on other planetary bodies.

Fatima Husain | EAPS | June 17, 2019 | mit
~5 mins   

Tags: eaps school-of-science dna mars planetary-science space-exploration microchips biology space astronomy-and-planetary-science research

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.

Karen Zusi | Broad Institute | June 12, 2019 | mit
~7 mins   

Tags: research crispr genome-editing rna dna genetics broad-institute mcgovern-institute biological-engineering brain-and-cognitive-sciences school-of-science school-of-engineering

Drug makes tumors more susceptible to chemo

Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.

Anne Trafton | MIT News Office | June 6, 2019 | mit
~7 mins   

Tags: research biology cancer dna drug-development drug-resistance koch-institute school-of-science medicine health-sciences-and-technology

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