How brain cells pick which connections to keep

Novel study shows protein CPG15 acts as a molecular proxy of experience to mark synapses for stabilization.

David Orenstein | Picower Institute for Learning and Memory | Aug. 6, 2019 | mit
~7 mins   

Tags: picower-institute brain-and-cognitive-sciences school-of-science neuroscience memory biology research proteins

Speeding up drug discovery for brain diseases

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.

Nicole Davis | July 31, 2019 | mit
~6 mins   

Tags: whitehead-institute picower-institute school-of-science behavior biology brain-and-cognitive-sciences crispr development disease genetics mental-health national-institutes-of-health-nih pharmaceuticals research proteins drug-development

Translating proteins into music, and back

By turning molecular structures into sounds, researchers gain insight into protein structures and create new variations.

David L. Chandler | MIT News Office | June 26, 2019 | mit
~8 mins   

Tags: research nanoscience-and-nanotechnology proteins civil-and-environmental-engineering school-of-engineering national-institutes-of-health-nih artificial-intelligence machine-learning music apps arts technology-and-society

Predicting sequence from structure

Researchers have devised a faster, more efficient way to design custom peptides and perturb protein-protein interactions.

Raleigh McElvery | Department of Biology | Feb. 15, 2019 | mit
~7 mins   

Tags: school-of-science biology biological-engineering cancer computer-modeling data disease drug-delivery health research proteins

Enhanced NMR reveals chemical structures in a fraction of the time

Technique could yield insights into complex proteins involved in Alzheimer’s and other diseases.

Anne Trafton | MIT News Office | Jan. 18, 2019 | mit
~5 mins   

Tags: research chemistry school-of-science proteins biology magnets imaging plasma-science-and-fusion-center

Researchers decode molecule that gives living tissues their flexibility | MIT News

Study reveals atomic structure of tropoelastin, showing what goes wrong in some diseases.

David L. Chandler | MIT News Office | June 25, 2018
~8 mins |

Tags:  research  biomaterials  biology  proteins  chemistry  school-of-engineering  civil-and-environmental-engineering  national-science-foundation-nsf  national-institutes-of-health-nih

Structure of key growth regulator revealed | MIT News

Researchers identify the molecular structure of the GATOR1 protein complex, which regulates growth signals in human cells, using cryo-electron microscopy.

Nicole Davis | Whitehead Institute | March 28, 2018
~6 mins |

Tags:  research  biology  proteins  whitehead-institute  school-of-science  national-institutes-of-health-nih  national-science-foundation-nsf  cells

New sensors can detect single protein molecules | MIT News

Modified carbon nanotubes could be used to track protein production by individual cells.

Anne Trafton | MIT News Office | Jan. 23, 2017
~5 mins |

Tags:  research  chemical-engineering  nanoscience-and-nanotechnology  proteins  sensors  school-of-engineering

Probing the function of key proteins | MIT News

Professor Barbara Imperiali creates better biochemical tools for basic biology and drug development.

Eric Bender | MIT Industrial Liaison Program | Jan. 12, 2017
~8 mins |

Tags:  faculty  profile  biology  chemistry  proteins  industry  startups  innovation-and-entrepreneurship-ie  medicine  drug-development  school-of-science  microbiology

Protein imaging reveals detailed brain architecture | MIT News

New technique could contribute to efforts to map the human brain.

Anne Trafton | MIT News Office | Dec. 3, 2015
~7 mins |

Tags:  research  imaging  microscopy  brain-and-cognitive-sciences  neuroscience  proteins  chemical-engineering  picower-institute  institute-for-medical-engineering-and-science-imes  school-of-engineering

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