1-alkylglycerophosphocholine_O-acyltransferase

1-alkylglycerophosphocholine O-acyltransferase

1-alkylglycerophosphocholine O-acyltransferase

Class of enzymes

In enzymology, a 1-alkylglycerophosphocholine O-acyltransferase (EC 2.3.1.63) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine CoA + 2-acyl-1-alkyl-sn-glycero-3-phosphocholine
Quick Facts Identifiers, EC no. ...

Thus, the two substrates of this enzyme are acyl-CoA and 1-alkyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and 2-acyl-1-alkyl-sn-glycero-3-phosphocholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase. This enzyme participates in ether lipid metabolism.

References

    • Waku K, Nakazawa Y (October 1970). "Acyltransferase activity to 1-O-alkyl-glycero-3-phosphorylcholine in sarcoplasmic reticulum". J. Biochem. 68 (4). Tokyo: 459–66. PMID 5488773.
    • Waku K, Nakazawa Y (August 1972). "Acyltransferae activity to 1-acyl-, 1-O-alkenyl-, and 1-O-alkyl-glycero-3-phosphorylcholine in Ehrlich ascites tumor cells". J. Biochem. 72 (2). Tokyo: 495–7. PMID 4644313.


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