This article contains information about the literary events and publications of 1533.

• October – The censors of the Collège de Sorbonne stigmatize François Rabelais' Pantagruel as obscene.
• date unknown – French poet Maurice Sceve announces that he has found the tomb of "Laura", the woman who is the subject of so many poems by Petrarch, at the church of Santa Croce in Avignon, further strengthening French interest in the Italian poet.^[1]

• January 2 – Johann Major, German poet and theologian (died 1600)
• January 3 – Jerónimo Bautista Lanuza, Spanish friar, bishop and homiletic writer (died 1624)
• June 6 – Bernardino Baldi, Italian mathematician, polymath and writer (died 1617)
• August 7 – Alonso de Ercilla, Spanish soldier and poet (died 1594)
• Unknown dates
  • Eknath, Marathi language religious poet in the Hindu tradition of India (died 1599)
  • Elazar ben Moshe Azikri, Jewish kabbalist, poet and writer (died 1600)
  • Andrea Rapicio, Italian poet writing in Latin (died 1573)^[2]
  • Sun Kehong (孫克弘), Chinese landscape painter, calligrapher and poet (died 1611)
  • (Or 1534) – Lucas Janszoon Waghenaer, Dutch cartographer (died 1606)

• July 6 – Ludovico Ariosto, Italian poet also writing Latin verse (born 1474)^[3]
• November 6 or 11 – Pieter Gillis, Flemish humanist, printer and Antwerp city official (born 1486)
• Unknown date – Giovanni Francesco Pico della Mirandola, Italian philosopher writing in Latin (born 1470)