The year 1727 in music involved some significant events.

• April 11 – Johann Sebastian Bach gives the première of his St Matthew Passion BWV 244b (BC D 3a) at St. Thomas Church, Leipzig
• Farinelli performs at Bologna, where he meets his mentor, Antonio Bernacchi.
• The Davidov-Morrini, ex General Dupont and Holroyd violins are made by Antonio Stradivari.
• Johann Adolph Hasse arrives in Venice.
• Louis-Claude Daquin is appointed organist at St Paul's in Paris.
• Agostino Steffani visits Italy for the last time, and meets Handel at the palace of Cardinal Ottoboni in Rome.
• George Frideric Handel is commissioned to write four anthems for the coronation ceremony of King George II of Great Britain.

• Joseph Bodin de Boismortier
  • 6 Suites à 2 Muzettes, Op. 11
  • 6 Concertos for 5 Flutes, Op. 15
  • 6 Suites à 2 Muzettes, Op. 17
• André Chéron – Sonates en trio, Op. 1
• Azzolino Bernardino Della Ciaia – Harpsichord Sonata in G major, Op. 4
• Girolamo Nicola Laurenti – 6 Concerti, Op. 1
• Michelle Mascitti – 8 Violin Sonatas and 4 Concertos à 6, Op. 7 (Paris)
• Antonio Vivaldi – La Cetra (The lyre) (Op. 9), 2 violin concertos and 1 for 2 violins (Amsterdam)
• Robert Woodcock – 12 Concertos in 8 parts

• Johann Sebastian Bach
  • Ach Gott, wie manches Herzeleid, BWV 58
  • Ein feste Burg ist unser Gott, BWV 80
  • Ich habe genug, BWV 82, premiered Feb. 2 in Leipzig
  • Ich bin vergnügt mit meinem Glücke, BWV 84
  • Ich lasse dich nicht, du segnest mich denn!, BWV 157
  • Dem Gerechten muss das Licht, BWV 195
  • Lass, Fürstin, lass noch einen Strahl, BWV 198
  • Matthäuspassion, BWV 244b
  • Partita in A minor, BWV 827
• Antonio Caldara – Il Batista
• Johann Joseph Fux – Laetare turba
• Christoph Graupner – Machet die Tore weit, GWV 1101/27
• George Frideric Handel
  • Coronation Anthems
  • Sonatas for an accompanied solo instrument, Op. 1 (published)
• Jean-Philippe Rameau – Nouvelles suites de pièces de clavecin
• Johan Helmich Roman – 12 Flute Sonatas, BeRI 201–212
• Giuseppe Sammartini – 12 Trio Sonatas
• Georg Philipp Telemann
  • 6 Sonatas, TWV 40:101–106
  • Trio Sonata, TWV 42:e7 (likely)
• Jan Dismas Zelenka
  • Credidi, ZWV 85
  • De profundis, ZWV 96
  • Lauda Jerusalem, ZWV 104
  • Magnificat, ZWV 107

• Antonio Bioni – Attalo ed Arsinoe
• Giovanni Bononcini – Astianatte
• George Frideric Handel
  • Admeto, Premiered Jan. 31 in London
  • Riccardo Primo
• Leonardo Leo – Il Cid
• Benedetto Marcello – Arianna
• Georg Reutter – Archidamia
• Leonardo Vinci – La caduta de' decemviri
• Antonio Vivaldi
  • Farnace (first premiered; this version was lost and the 1731 Pavia version is the only one extant today)^[1]
  • Ipermestra, RV 722
  • Orlando
  • Siroe re di Persia, RV 735

• Ernst Gottlieb Baron – Historisch-theoretische und practische Untersuchung des Instruments der Lauten
• Giuseppe Graziani – Continuazione, e supplemento alla drammaturgia di M. L. Allacci^[2]

• February 25 – Armand-Louis Couperin, organist, harpsichordist and composer (died 1789)
• March 9 – Johann Gottlieb Preller, cantor and composer (died 1786)
• March 14 – Johann Gottlieb Goldberg, harpsichordist, organist and composer (died 1756)
• March 22 – Niel Gow, fiddler and composer (died 1807)
• March 30 – Tommaso Traetta, composer (died 1779)
• April 5 – Pasquale Anfossi, opera composer (died 1797)
• April 29 – Jean-Georges Noverre, a founder of modern ballet (died 1810)
• October 9 – Johann Wilhelm Hertel
• date unknown
  • Marie Favart, singer, dancer and actress (died 1772)
  • Rosa Scarlatti, opera singer (died 1775)

• February 22 – Francesco Gasparini, composer (born 1661)
• May – Daniel Roseingrave, organist and composer (born c. 1655)
• August 14 – William Croft, organist and composer (born 1678)^[3]
• December 1 – Johann Heinrich Buttstett, organist and composer (born 1666)