1960 Preseason

The CFL played an unbalanced schedule of Exhibition games.

Four teams (Ottawa, Toronto, Winnipeg and Hamilton) played their annual split-squad scrimmages at the conclusion of their preliminary training camps.

25 players received skin burns during an Edmonton–Calgary game played at Mewata Stadium in Calgary on July 20. Two Eskimos, Roger Nelson and Jim Shipka, were treated in a Calgary hospital. Two Stampeders, Doug Brown and Ernest Warlick, filed damage claims with the City of Calgary. The lime used for field markings initially was suspected as being the cause, although laboratory tests later determined it was fully hydrated and should not have been the culprit. Fertilizer also was suggested as a possible cause of the skin burns.

On July 28, the Saskatchewan Roughriders played the London Lords of the Senior Ontario Rugby Football Union in London, Ontario, and beat their hosts 38–0.

On July 29, the BC Lions played the Winnipeg Blue Bombers in Cedar Rapids, Iowa. Part of the local appeal was the presence on three former University of Iowa stars, Kenny Ploen and Ray Jauch of the Blue Bombers, and Willie Fleming of the BC Lions.

After playing (and losing to) the NFL Chicago Cardinals in 1959, the Toronto Argonauts hosted the NFL Pittsburgh Steelers at CNE Stadium on August 3 and lost 43–16. Both teams used 12 players, with a handful of NFL rules (blocking, punt returns) blended into the Canadian game.

Toronto also played host to an NFL exhibition game between the Chicago Bears and the New York Giants, at Varsity Stadium on Monday, August 15. Top ticket price was $10, which was the most ever charged for a non-Grey Cup game in Toronto. George Halas of the Bears, who also served as chairman of the NFL's expansion committee, admitted that in 1961 the NFL would have 14 teams, an awkward number, and that 16 teams would be more convenient for scheduling. It was suggested that this game was a trial balloon for a possible expansion team in Toronto. Chicago defeated the Giants by a 16–7 score, but the paid attendance was only 5,401, handing the promoters a $30,000 loss and effectively ending any chance of an NFL team north of the border.

1960 regular season

Coaching Changes

Calgary

• Fri 19 August – Otis Douglas resigns as head coach of the Calgary Stampeders, after the club started the season with a tie and two losses. General Manager Jim Finks acts as co-ordinator of coaches for Calgary's August 22 game versus the BC Lions (a loss).
• Tue 23 August – Steve Owen is appointed head coach for the remainder of the 1960 season.

General Manager Changes

Edmonton

• Sat 10 September – Keith Rolfe resigns as General Manager of the Edmonton Eskimos, to take a position with an oil company in Calgary. Joe Ryan, formerly with the Toronto Argonauts, is named as his successor.

Final regular season standings

Note: GP = Games Played, W = Wins, L = Losses, T = Ties, PF = Points For, PA = Points Against, Pts = Points

• Bold text means that they have clinched the playoffs.
• Winnipeg and Toronto have first round byes.

Conference Semi-Finals

Conference finals

Grey Cup Championship