The 1999–2000 NBA season was the San Antonio Spurs' 24th season in the National Basketball Association, their 27th season as the Spurs, and their 33rd season as a franchise.^[1] After having won their first NBA championship in 1999, where they defeated the #8 seed New York Knicks in five games, the Spurs signed free agents Terry Porter,^[2][3][4][5] Samaki Walker and Chucky Brown during the off-season.^[6][7][8] However, prior to the season, Sean Elliott was diagnosed with a kidney disorder, and missed the first four months of the season; he would then receive a kidney transplant from his brother, Noel.^{[9][10][11][12][13]} The Spurs were originally scheduled to play two games against the Minnesota Timberwolves overseas in Tokyo, Japan in November during the first month of the regular season, but because they won the NBA championship, they were obligated to play in the McDonald's Championship in Milan, Italy in October.^[14][15][16]

In 1999-2000, the Spurs won 14 of their first 17 games, including a 7-game winning streak.^[17] The team held a 32–17 record at the All-Star break,^[18] with Tim Duncan and David Robinson both being selected for the 2000 NBA All-Star Game,^[19][20][21] where Duncan and Shaquille O'Neal of the Los Angeles Lakers were both named co-MVP's.^{[22][23][24][25][26]} At midseason, Brown was released to free agency and re-signed with the Charlotte Hornets. On March 14, 2000, the Spurs' playoff spirits would get a lift when Elliott returned to play in a 94–79 home win over the Atlanta Hawks, and played in the final 19 games.^{[27][28][29][30]} However, as the season wound down, Duncan suffered a knee injury,^{[31][32][33][34]} as the Spurs finished second in the Midwest Division with a 53–29 record.^[35] Without Duncan, they were eliminated in the Western Conference First Round of the playoffs by the 5th-seeded Phoenix Suns in four games.^{[36][37][38][39]}

Duncan averaged 23.2 points, 12.4 rebounds and 2.2 blocks per game, and was named to the All-NBA First Team, and to the NBA All-Defensive First Team, while Robinson averaged 17.8 points, 9.6 rebounds and 2.3 blocks per game, and was selected to the All-NBA Third Team. In addition, Avery Johnson provided the team with 11.2 points and 6.0 assists per game, while Porter contributed 9.4 points per game off the bench, Mario Elie provided with 7.5 points per game, and Malik Rose averaged 6.7 points and 4.5 rebounds per game off the bench.^[40] Duncan also finished in fifth place in Most Valuable Player voting.^[41][42][43]

Following the season, Elie signed as a free agent with the Phoenix Suns,^[44][45][46] and Jerome Kersey signed with the Milwaukee Bucks during the next season.^[47]

• Tim Duncan, All-NBA First Team
• David Robinson, All-NBA Third Team
• Tim Duncan, NBA All-Defensive First Team