2-dehydro-3-deoxy-L-arabinonate_dehydratase

2-dehydro-3-deoxy-L-arabinonate dehydratase

2-dehydro-3-deoxy-L-arabinonate dehydratase

Class of enzymes


The enzyme 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) catalyzes the chemical reaction

2-dehydro-3-deoxy-L-arabinonate 2,5-dioxopentanoate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming). Other names in common use include 2-keto-3-deoxy-L-arabinonate dehydratase, and 2-dehydro-3-deoxy-L-arabinonate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.


References

    • Stoolmiller AC, Abeles RH (1966). "Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila". J. Biol. Chem. 241 (24): 5764–71. PMID 5954356.



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