The 2001 MTV Europe Music Awards were held in The Festhalle, Frankfurt. The ceremony attracted the largest television audience for the awards until 2007 and was one of the first entertainment broadcasts following the September 11 attacks in New York City.

Performances included Blink-182 with "First Date", Depeche Mode with "Never Let Me Down Again", Rammstein with "Ich Will" and Kylie Minogue with "Can't Get You Out of My Head". Jay-Z performed his track "Girls, Girls, Girls" and Craig David took to the stage with a version of "Walking Away" that sampled U2's "One".

The presenter line up included actress Christina Ricci, girl group Atomic Kitten, Nelly Furtado, Sugababes and Claudia Schiffer.

Winners are in bold text.

Winners are in bold text.

• Kylie Minogue — "Can't Get You Out of My Head"
• Dido — "Hunter"
• Basement Jaxx — "Where's Your Head At"
• Blink-182 — "First Date"
• Craig David — "Walking Away"
• Mary J. Blige — "Family Affair"
• Jay-Z — "Izzo (H.O.V.A.) / Girls, Girls, Girls"
• Depeche Mode — "Never Let Me Down Again"
• Fred Durst, Wes Scantlin and Jimmy Page — "Thank You"
• Rammstein — "Ich Will"
• R.E.M. — "Imitation Of Life"
• Travis — "Side"

• Ben Stiller and Claudia Schiffer — presented Best Group
• Emma Bunton and Eddy Grant — presented Best Male
• Sophie Ellis-Bextor and Bomfunk MC's — presented Best Dance
• Kelis and Gavin Rossdale — presented Best Female
• Pink and Pedro Almodóvar — presented Best Video
• Sugababes and Roger Sanchez — presented The Web Award
• Heidi Klum and Boris Becker — presented Best R&B
• Xavier Naidoo and Nelly Furtado — presented Best Hip-Hop
• Joshua Jackson — presented Free Your Mind Award
• Christina Ricci — presented Best Album
• Nina Persson and Herbert Gronemeyer — presented Best Pop
• Shaggy and Andrea Corr — presented Best New Act
• Atomic Kitten and Ronan Keating — presented Best Rock
• Alicia Keys and Brendan B. Brown — presented Best Song

• 2001 MTV Video Music Awards

• Nominees