The 2006 Teen Choice Awards ceremony was held on August 20, 2006, at the Gibson Amphitheatre, Universal City, California. The event was hosted by Dane Cook and Jessica Simpson,^[1] and featured performances by Nelly Furtado and Timbaland, Rihanna, and Kevin Federline, who made his television performance debut as the night's headlining act.

Fall Out Boy was the most-awarded nominee in the Music categories, winning three awards for Choice Single, Rock Group, and Rock Track respectively. Pirates of the Caribbean: Dead Man's Chest led the film nominees with six awards, including for Choice Action Adventure. High School Musical topped the television nominees, also earning three wins, including Choice Comedy/Musical. The Courage Award was presented to Jason McElwain, a high school basketball team manager with autism, for his athletic performance at the end of a division game that won his team the match.^[2]

• Nelly Furtado and Timbaland – "Promiscuous"^[2]
• Rihanna – "SOS"^[2]
• Kevin Federline – closed the show with the television debut of his single "Lose Control"^[2]

Voting took place via the Teen People, MySpace, IGN, and Fox websites,^[6] and ended on August 11, 2006.^[1] with 14.7 million votes cast.^[2] Pirates of the Caribbean: Dead Man's Chest received the most nominations in the Movies categories, and overall, with nine. Everybody Hates Chris led the Television categories with six nominations, followed by Grey's Anatomy, Smallville, and The O.C. with five each. Rihanna was the most-nominated Music act, earning six nominations, while Shakira and Sean Paul tied with four apiece.^[6]

Winners are listed first and highlighted in bold.^[2]