USC

WMU opened the season with a 49–31 loss to No. 4 USC. Despite losing by 18 points, USC struggled to stop WMU's running game^[9] as the Broncos led the Trojans in team rushing yards 263–232 and led time of possession 34:40–25:20.^[10] WMU also led the game 21–14 with 9:11 left in the third quarter and the game was tied at 28 with 7:54 left.^[11] Redshirt freshman Jon Wassink started the game at quarterback for WMU and caught a touchdown pass and also rushed for a touchdown. Senior cornerback and kick returner Darius Phillips intercepted a pass and returned a kickoff 100 yards for a touchdown.

Michigan State

The Broncos traveled to face Michigan State in East Lansing on September 9. The WMU offense struggled throughout as the MSU defense held the Broncos to 195 yard on offense. The only bright spot for the Broncos was Phillips who forced a fumble and returned it 67 yards for a touchdown early in the third quarter to cut the Spartans lead to 14–7. After the Spartans moved the lead to 28–7 on an LJ Scott two-yard touchdown run, Phillips answered again, returning the ensuing kickoff 100 yards for the Broncos second touchdown of the game.^[12] MSU's defense took over from there, halting the last WMU drive on fourth down at the Spartan 15 yard line.^[13]

Idaho

The Broncos welcomed the Vandals to Waldo Stadium on September 16 for the team's first home game. The Broncos trailed 14–6 at the half and 28–19 as the third quarter ended as they looked like they were headed for their third consecutive defeat to open the season. However, John Wassink ran for two scores in the fourth quarter and the Broncos added a field goal to pull out the win 37–28.^[14]

Wagner

WMU finished the non-conference portion of their schedule against Wagner at Waldo Stadium. Quarterback Jon Wassink threw a career-high three touchdown passes as the Broncos blew out the Eagles 49–14. WMU racked up 527 total yards while limiting Wagner to 113 yards. The win moved WMU to 2–2 on the season.^[15]

Ball State

The Broncos began the MAC season with a bang, blowing out Ball State 55–3. Wassink again threw three touchdown passes as the Broncos Obbie Jackson recovered a fumble on the opening kickoff and returned it 21 yards for a touchdown to get the Broncos started. The Broncos out-gained the Cardinals 414–238 as they forced two Ball State turnovers. The win moved the Broncos to 3–2 on the season.^[16]

Buffalo

The Broncos defeated Buffalo 71–68 in seven overtimes in a game that broke the record for most points in an NCAA Division I Football Bowl Subdivision (FBS) game and tied the record for most overtime (OT) periods in a single game.^[17] The 139 points beat the previous record of 137 points scored by Pittsburgh and Syracuse in 2016.

WMU had a 10 point lead early in the fourth quarter before Buffalo scored touchdowns on consecutive drives to take a 4 point lead. WMU regained the lead with 4:45 to go in regulation with a touchdown to tight end Donnie Ernsberger. Buffalo tied the game with a 34 yard field goal with 34 seconds left. WMU had a chance to win the game with a 52 yard field goal, but it was blocked and the game entered OT 31–31.^[18]

In OT, each team had opportunities to win the game. In the third OT, Buffalo turned the ball over with a fumble, but WMU missed a 29 yard field goal that would have won the game. In the fifth OT, WMU scored a touchdown but failed on the two-point conversion. Buffalo also scored a touchdown and failed on the two-point conversion that would have won the game. In the seventh and final OT, Buffalo had to settled for a field goal and WMU won the game with a Jarvion Franklin 12 yard touchdown run.

Akron

In a game that was postponed a day due to heavy flooding in Waldo Stadium, WMU lost to Akron 14–13.^[19] The Broncos trailed 14–3 at halftime and could only score 10 points in the 4th quarter. WMU had the ball with 45 seconds left in the game and drove to the Akron 39 yard line, but could not attempt a 56-yard field goal before time expired. Franklin led the Broncos with 130 yards rushing on 31 carries.^[20] WMU outgained Akron 426 total yards to 215.

After the game was postponed, 1 to 1.4 million gallons of water were removed from the field overnight.^[21] The game was originally scheduled to be broadcast on the CBS Sports Network (CBSSN), but due to the postponement, was not televised. This was the first MAC game to be played on a Sunday since 2006.^[21]

Eastern Michigan

The following week, the Broncos traveled to face rival Eastern Michigan. After taking a 10–7 lead at halftime, Jarvion Franklin's seven-yard rush gave the Broncos a 17–10 lead heading into the fourth quarter. However, the Eagles tied it up early in the fourth quarter and moved in to field goal range as the clock was running out. A 37-yard field goal attempt was no good as time expired to send the game in to overtime. In overtime, WMU was forced to settle for a field goal and the Bronco defense prevented the Eagles from scoring a touchdown. The Eagles missed another field goal, this one from 24 yards out, to give the Broncos the 20–17 win. Franklin rushed for 104 yards and a touchdown in the game as the Broncos moved to 5–3 on the season.^[22]

Central Michigan

The Broncos jumped out early to a 14–0 lead against rival Central Michigan. They took a 21–7 lead at the half on the strength of three rushing touchdowns. Jarvion Franklin's second touchdown of the game gave the WMU a 28–14 lead with just over eight minutes remaining in the third quarter. However, the Chippewas roared back, scoring touchdowns on three of their next four possessions to pull out the 35–28 win and earn the Cannon Trophy. The loss dropped WMU to 5–4 on the season.^[23]

Kent State

As Western Michigan returned home to take on Kent State, the Bronco defense took control of the game. Scoring three touchdowns on two interception returns and one fumble return, the Bronco defense helped give WMU the easy 48–20 win. Jarvion Franklin rushed for 191 yards including a 72-yard touchdown run to give the Broncos the lead for good as the first quarter ended. In addition to scoring three touchdowns, the Bronco defense limited the Golden Flashes to 281 yards in the game. The win moved the Broncos to 6–4 on the season and made them bowl eligible.^[24]

Northern Illinois

On a windy Wednesday night game, the Broncos traveled to DeKalb to face Northern Illinois. Jarvion Franklin rushed for 115 yards and a touchdown in the game, but the Broncos still trailed 21–14 at the half. WMU took the lead in the third on a Reece Goddard touchdown run and pass to give the Broncos a 28–21 lead going into the fourth quarter. However, NIU scored twice in the fourth quarter and the Broncos could only manage a field goal as WMU fell 35–31. The loss dropped the Broncos to 6–5 on the season and ended any chance to win the MAC East Division.^[25][26]

Toledo

In the final regular season game, the Broncos traveled to Toledo as the Rockets looked to clinch a trip to the MAC Championship. The Rockets manhandled the Broncos, taking a 24–3 lead early in the third quarter. A Tyron Arnett 26-yard touchdown pass from Reece Goddard narrowed the lead to 24–10 with four minutes left in the third, but the Broncos could not score again as Toledo clinched the MAC West division with a 37–10 win. The loss dropped the Broncos to 6–6 on the season.^[27][28]