23S_rRNA_(cytidine2498-2'-O)-methyltransferase

23S rRNA (cytidine2498-2'-O)-methyltransferase

23S rRNA (cytidine2498-2'-O)-methyltransferase

Class of enzymes


23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytidine2498 in 23S rRNA S-adenosyl-L-homocysteine + 2'-O-methylcytidine2498 in 23S rRNA
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References

  1. Purta E, O'Connor M, Bujnicki JM, Douthwaite S (June 2009). "YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA". Molecular Microbiology. 72 (5): 1147–58. doi:10.1111/j.1365-2958.2009.06709.x. PMID 19400805.

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