3-hydroxykynurenine

3-Hydroxykynurenine

3-Hydroxykynurenine

Chemical compound

3-Hydroxykynurenine is a metabolite of tryptophan, which filters UV light in the human lens.[1] It is one of two pigments identified as responsible for the goldenrod crab spider's (Misumena vatia) yellow coloration.

The Kynurenine pathway, which connects quinolinic acid to tryptophan. The pathway is named for the first intermediate, kynurenine, which is a precursor to kynurenic acid and 3-hydroxykynurenine.[2]
Quick Facts Names, Identifiers ...

References

  1. [1]
    Malina, HZ; Martin, XD (1995). "Deamination of 3-hydroxykynurenine in bovine lenses: a possible mechanism of cataract formation in general". Graefes Arch Clin Exp Ophthalmol. 233 (1): 38–44. doi:10.1007/bf00177784. PMID 7721122. S2CID 25414197.
  2. [2]
    Schwarcz, Robert; John P. Bruno; Paul J. Muchowski; Hui-Qiu Wu (July 2012). "Kynurenines in the Mammalian Brain: When Physiology Meets Pathology". Nature Reviews Neuroscience. 13 (7): 465–477. doi:10.1038/nrn3257. PMC 3681811. PMID 22678511.

See also


Stub icon

This article about an organic compound is a stub. You can help Wikipedia by expanding it.
Share this article:

This article uses material from the Wikipedia article 3-hydroxykynurenine, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.