4-methyl-GHB

<i>gamma</i>-Hydroxyvaleric acid

gamma-Hydroxyvaleric acid

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γ-Hydroxyvaleric acid (GHV), also known as 4-methyl-GHB, is a designer drug related to γ-hydroxybutyric acid (GHB). It is sometimes seen on the grey market as a legal alternative to GHB, but with lower potency and higher toxicity,[2] properties which have tended to limit its recreational use.[3]

Quick Facts Clinical data, Other names ...

γ-Valerolactone (GVL) acts as a prodrug to GHV, analogously to how γ-butyrolactone (GBL) is a prodrug to GHB.[4]

See also

References

  1. [1]
    "GHB and Analogues: Fast Facts". National Drug Intelligence Center. January 1, 2006. Archived from the original on July 26, 2023. Retrieved July 5, 2023.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  2. [2]
    Carter LP, Chen W, Wu H, Mehta AK, Hernandez RJ, Ticku MK, et al. (April 2005). "Comparison of the behavioral effects of gamma-hydroxybutyric acid (GHB) and its 4-methyl-substituted analog, gamma-hydroxyvaleric acid (GHV)". Drug and Alcohol Dependence. 78 (1): 91–99. doi:10.1016/j.drugalcdep.2004.10.002. PMID 15769562.
  3. [3]
    Smith F (31 December 2004). Handbook of Forensic Drug Analysis. Academic Press. pp. 462–. ISBN 978-0-08-047289-8.
  4. [4]
    Andresen-Streichert H, Jungen H, Gehl A, Müller A, Iwersen-Bergmann S (May 2013). "Uptake of gamma-valerolactone--detection of gamma-hydroxyvaleric acid in human urine samples". Journal of Analytical Toxicology. 37 (4): 250–254. doi:10.1093/jat/bkt013. PMID 23486087.
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