The Milwaukee Mile in West Allis, Wisconsin has hosted American open-wheel car racing events dating back to 1937. The AAA Contest Board, USAC, CART, Champ Car World Series, and the IndyCar Series have all sanctioned races at the facility. The Milwaukee Mile has a long history of Championship/Indy car racing, and for many years, traditionally held a race the weekend after the Indianapolis 500.

The NTT IndyCar Series first held events at Milwaukee from 2004 to 2009, and again from 2011 to 2015. The most recent race (2015), was called the ABC Supply Wisconsin 250. After an eight-year hiatus, the IndyCar Series is scheduled to return for a doubleheader in 2024.^[1]

Open wheel racing at the track dates back to 1937. AAA sanctioned races in 1937–1939, 1941, and 1946–1955. The track was paved in 1954. For most years starting in 1949, Milwaukee traditionally hosted the first race following the Indianapolis 500. From 1947 to 1982, Milwaukee normally hosted two races, the first race right after Indy in early June, and the second in August or September. The latter sometimes in the days surrounding the Wisconsin State Fair.

USAC sanctioned Championship car races from 1956 to 1979. In 1980, the race switched to a CART (later CCWS) race, and continued through 2006. After the 1982 season, the second race was dropped.^[2] With only one race annually going forward, the track decided to keep the traditional June "right after Indy" date. This tradition was famously referenced in the 1969 movie Winning where Robert Wagner's character delivered the line "Everybody goes to Milwaukee after Indianapolis".^[3] In 1986, the race was scheduled for Sunday June 1. However, due to rain on May 25–26, the Indianapolis 500 was postponed to Saturday May 31. After discussions with track, television, and series leaders, the Milwaukee race was pushed back one week to make the accommodation.

The IRL/IndyCar Series started holding races at the track in 2004, and thus for a brief time (2004–2006), the track hosted both a Champ Car race (June) and an IndyCar race (late July). For 2007, IndyCar became the lone event. At that time, there was a renewed interest in placing the event on its traditional June date immediately after the Indy 500. This arrangement lasted three years (2007–2009). The race was put on hiatus for 2010, stemming from management difficulties regarding payment of sanctioning fees. In 2011, the race returned with Michael Andretti and Andretti Sports Marketing promoting the event. The race was branded as the Milwaukee Indyfest and included an infield festival reminiscent of street racing formats with vendors, paddock access, music stages, family zones and the signature Ferris Wheel. The Milwaukee IndyFest ran for four years, with ABC Supply Co joining as the Title Sponsor in 2013.

In 2011–2013, for a variety of reasons, race organizers decided to move the race to the Saturday of Father's Day weekend. Detroit took the weekend immediately after Indy, and Texas maintained its position on the second weekend of June. For 2014, the race moved to August reviving the old state fair date. For 2015, it moved back to July, then went on hiatus due to poor revenue and poor attendance. After eight years, and after track renovations, the race is scheduled to return in 2024 as a doubleheader on Labor Day weekend.