Abd Manaf al-Mughirah ibn Qusai (Arabic: عبد مناف ٱلمغيرة بن قصي, ʿAbd Manāf al-Mughīrah ibn Quṣayy) was a Qurayshi and great-great-grandfather of the Islamic prophet Muhammad. His father was Quṣai ibn Kilāb.

Abd Manaf was already honoured in his father's lifetime however Qusai preferred his first-born 'Abd ad-Dar and invested him with all his rights, powers, and transferred the ownership of the House of Assembly shortly before his death.^[1]

After Quṣayy's death, Abd Manaf contested this inheritance. He was supported by their nephew Asad, their uncle Zuhrah ibn Kilab, their father's uncle Taym ibn Murrah (of Banu Taym), and al-Harith ibn Fihr, while 'Abd ad-Dar was supported by their cousins Makhzum, Sahm, Jumah, their uncle Adi and their families. The effects of this conflict continued among their descendants, especially under Abd Manaf's son Hashim and affected the internal history of Mecca right up to Muhammad's time.^[2]

Abdu Manaf married several wives of influential tribes, including 'Ātikah bint Murrah ibn Hilāl ibn Fālij ibn Dhakwān ibn Hilal ibn Sa'sa'ah ibn Mu'awiyah ibn Bakr ibn Hawazin al-Hilaliyya of Bani Qays Aylan, Hilal of the Banu Bakr ibn Hawāzin, Raytah of Ta'if, and Waqida bint Amr.

Abd Manaf had three wives:

1. Atikah bint Murrah al-Hulaliyya

• a. Muttalib ibn Abd Manaf, Founder/ancestor of Banu Muttalib
• b. Amr-al-Ula/Hashim ibn Abd Manaf, Founder/ancestor of Banu Hashim
• c. Abd Shams/Qays-al-Ula ibn Abd Manaf, Founder/ancestor of Banu Abd Shams
• d. Tumadir bint Abd Manaf al-Quraishiyya
• e. Qilabah bint Abd Manaf al-Quraishiyya
• f. Hayyah bint Abd Manaf al-Quraishiyya
• g. Rayta bint Abd Manaf al-Quraishiyya
• h. Khathma bint Abd Manaf al-Quraishiyya
• i. Sufyanah bint Abd Manaf al-Quraishiyya

2. Rayta bint Ku'ayb al-Thaqafiyya

• a. Abd ibn Abd Manaf
• b. Abd-al-Amr ibn Abd Manaf

3. Waqidah bint Amr al-Qurayshiyya al-Amiriyya

• Nawfal ibn Abd Manaf, Founder/ancestor of Banu Nawfal

The grave of Abd Manaf can be found in Jannatul Mualla cemetery, in Mecca.^{[citation needed]}

• Abd Manaf (name)
• Family tree of Muhammad
• List of notable Hijazis