Cool & Dre are a record production and songwriting duo from North Miami, Florida, consisting of Marcello "Cool" Antonio Valenzano and Andre "Dre" Christopher Lyon. The duo were first discovered by New York rapper Fat Joe and began their careers working in tandem to produce his albums Jealous Ones Still Envy (2001) and Loyalty (2002). Two years later, they produced the hit song "New York" by Ja Rule, and "Hate It or Love It" by the Game the following year, which peaked at numbers 27 and two on the Billboard Hot 100, respectively. Cool & Dre were later credited on the Billboard 200 number-one albums Tha Carter III (2008), Tha Carter IV (2011), and Tha Carter V (2018) by Lil Wayne, as well as the collaborative album, Everything Is Love (2018) by Jay-Z and Beyoncé, which won a Grammy Award.^[1]

This biography of a living person needs additional citations for verification. (April 2020)

The duo have also worked extensively with rappers the Game, Nas, Queen Latifah, Ja Rule, Rick Ross, Remy Ma, and Kendrick Lamar, among others. Their credits include the former and 50 Cent's Grammy-nominated 2005 single, "Hate It or Love It", Juvenile's "Rodeo", Ja Rule's "New York", Fat Joe's Grammy-nominated 2016 hit, “All the Way Up", and Lil Wayne's "On Fire".

To date, their productions have sold over 75 million records worldwide.

Cool & Dre launched the record label Epidemic in 2004, through which they signed Florida rapper Kent Jones in a joint venture with DJ Khaled's We the Best Music Group and Epic Records. The labels released his 2016 debut single, "Don't Mind", which peaked at number eight on the Billboard Hot 100 and sold over two million units.^[2] Thereafter, they signed other Florida-based rappers Eric Leon (from Vero Beach) and Tom G (from Tampa).^[3]