Antiprotozoal agents (ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection.

A paraphyletic group, protozoans have little in common with each other. For example, Entamoeba histolytica, a unikont eukaryotic organism, is more closely related to Homo sapiens (humans), which also belongs to the unikont phylogenetic group, than it is to Naegleria fowleri, a "protozoan" bikont. As a result, agents effective against one pathogen may not be effective against another.

Antiprotozoal agents can be grouped by mechanism[1] or by organism.[2] Recent papers have also proposed the use of viruses to treat infections caused by protozoa.[3][4]

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